Project Grant R41ES038048
- The National Institute of Environmental Health Sciences (NIEHS) awarded Nexilico, Inc. a $275,765 Project Grant (CFDA 93.113 - Environmental Health) to develop a predictive computational-experimental platform to characterize microbial biotransformation of xenobiotic compounds and identify naturally occurring gut microbial strains that can mitigate xenobiotic toxicity as novel probiotics. The project aims to provide cost-effective yet accurate predictions to identify microbial species capable...
- This Project Grant award, valued at $646,476.00, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113). The overarching goal of the research is to understand how environmental chemicals, such as inorganic arsenic, trigger deregulation of the epigenome that can resist epigenetic reprogramming in germ cells and become heritable. The award supports a study leveraging a model of germ cell reprogramming based...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) Federal Grant Program provides $379,504 to the University System of New Hampshire's Keene State College to conduct research on the tissue-specific development of toxicity in response to transgenerational chronic arsenic exposures. The key objectives are to: (1) detect tissue-specific uptake of arsenic in response to transgenerational chronic exposure; (2)...
- This federal Project Grant award of $445,240 from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), supports research investigating the complex interactions between prenatal metal exposures, gut microbiome composition, and telomere length attrition in childhood. The research, conducted by the Icahn School of Medicine at Mount Sinai, aims to better understand how environmental exposures and the gut microbiome...
- This Project Grant award from the Department of Health and Human Services National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) is focused on defining the molecular target of arsine gas-induced acute kidney injury and associated morbidity. The $222,750 award, provided from June 2025 to May 2027, supports research by the University of Alabama at Birmingham (UAB) to investigate the pathogenic molecular mechanisms underlying arsine gas-induced hemolysis...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), will support Framergy, Inc., in collaboration with Texas A&M University, to develop a simple and low-cost method for detecting a broad range of per- and polyfluoroalkyl substances (PFAS) that can be used as an at-home test kit. The $260,993 award, granted on June 1, 2025, will fund research to leverage novel metal-organic framework...
- This Project Grant award, totaling $306,789, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113). The grant aims to develop an at-home lateral flow assay (LFA) system for rapid, low-cost detection of per- and polyfluoroalkyl substances (PFAS) in water samples. The innovative approach integrates a magnetic nanoparticle pre-concentration method to achieve the sensitivity required by EPA standards, down...
- The National Institute of Environmental Health Sciences (NIEHS) awarded a $147,486 Project Grant under the Environmental Health federal grant program (CFDA 93.113) to Trustees of Boston University (doing business as Boston University Medical Campus) to conduct research on the associations between metal exposures, the urinary microbiome, and kidney health among adolescents in Central America. The 3-year longitudinal study, titled "Metals, the Microbiome, and Kidney Health among Adolescents...
- This $5,453,538 Project Grant was awarded on September 15, 2025 by the National Institute of Environmental Health Sciences (NIEHS), which administers the Environmental Health federal grant program (CFDA 93.113). The grant was awarded to New York University School of Medicine to investigate the accumulation of micro- and nanoplastic particles in mammalian tissues, including human exposure pathways, tissue deposition, and potential health impacts. Key objectives include quantifying MNP...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), awarded a $306,842 project grant to Anchorchem LLC on Jul 19, 2025. The grant aims to address the global health threat posed by harmful algal blooms (HABs) and the associated risks from cyanopeptides, specifically anabaenopeptins (ABPs). The project seeks to create a stable supply chain of these compounds to enable critical biological studies needed to assess their...
This Project Grant award of $306,374 from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health Federal Grant Program (CFDA 93.113) aims to develop novel microbiome-based solutions to reduce exposure to inorganic arsenic, a toxic heavy metal with widespread environmental contamination. The two-year project, running from September 2025 to August 2026, will focus on screening and optimizing gut bacterial strains to enhance arsenic metabolism and excretion, with the goal of mitigating arsenic toxicity. The award recipient, Luxbiome Inc., will pursue this research through in vitro screening and in vivo evaluation in mouse models. This work seeks to address the significant public health risks posed by chronic arsenic exposure, which is linked to cardiovascular disease, neurological disorders, diabetes, and various cancers.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $306.4k | 9/9/25 |