Project Grant R37CA303960
- The Leland Stanford Junior University was awarded a $1,108,391.72 Project Grant from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) with a project period from January 1, 2025 to December 31, 2027. The grant supports research to define the most therapeutically relevant CAR T cell subsets in patients with large B cell lymphoma (LBCL) and overcome immune suppression mechanisms of resistance to CAR T cell therapy. Key research activities include following...
- The National Cancer Institute awarded a $226,608 Project Grant under the Cancer Research Manpower program (CFDA 93.398) to The Leland Stanford Junior University (Stanford University) on December 17, 2024. The grant supports a project titled "INTEGRATING HIGHLY MULTIPLEXED IMMUNOFLUORESCENCE WITH LABEL-FREE 2D HYPERSPECTRAL CHEMICAL IMAGING TO INTERROGATE THE COLORECTAL CANCER TUMOR-INVASIVE FRONT". The project aims to develop a computational workflow that integrates advanced imaging...
- The Leland Stanford Junior University (Stanford University) has been awarded a $462,860 Project Grant from the National Cancer Institute (NCI), an institute of the U.S. Department of Health and Human Services, under the NCI's Cancer Treatment Research program (CFDA 93.395). This 5-year grant supports the development of novel targeted radionuclide therapy (TRT) approaches for the treatment of triple-negative breast cancer (TNBC). The key objectives of this project are to develop MUC1-targeted...
- This federal Project Grant award from the National Cancer Institute (CFDA 93.398 - Cancer Research Manpower) provides $119,172 to The Leland Stanford Junior University (Stanford University) from August 1, 2025 to July 31, 2027. The project aims to harness multi-modal and multi-omics data integration to decipher therapeutic response in non-small cell lung cancer. The research seeks to characterize the spatial interactions between tumor cells and their microenvironment using high-dimensional,...
- This federal Project Grant award of $584,521 was provided by the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) to The Leland Stanford Junior University (Stanford University) on August 8, 2025. The grant supports a research study to understand the non-genetic mechanisms that enable subclonal tumor populations to survive radiotherapy for soft tissue sarcomas. The key objectives are to: 1) identify and validate epigenetic changes that cause subclonal radioresistance, 2) define...
- This Cooperative Agreement awarded by the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) provides $1,281,520.00 in funding to The Leland Stanford Junior University to conduct research on the fundamental biological mechanisms of cancer metastasis, organ tropism, and immune evasion. The project aims to integrate genetic barcoding with single-cell profiling to uncover the key molecular drivers underlying metastatic fitness and diverse cancer cell states in pancreatic ductal...
- This $926,400 Project Grant was awarded by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program to The Leland Stanford Junior University. The grant will fund a 3-year research project to conduct an "Integrated Immunophenotypic Transcriptomic and Epigenomic Characterization of Uterine Mesenchymal Neoplasms with Expert Pathologist Panel Review". The objectives are to advance scientific understanding and develop new treatments for these...
- This federal Project Grant award, valued at $469,381.00, was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to The Leland Stanford Junior University. The award period runs from April 15, 2025 to April 14, 2027. The purpose of this grant is to fund research focused on "ENGINEERING CYTOTOXIC LYMPHOCYTES TO INFILTRATE OVARIAN CANCER TUMORS VIA METABOLITE-SENSING RECEPTORS". This advanced biomedical research aims to transform...
- This federal Project Grant award of $1,033,055.00 was provided by the Department of Health and Human Services National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The funding supports research aimed at understanding and targeting the mechanisms of cancer metastasis. The project, titled "Targeting Cancer Metastasis by Inhibiting Curvature-Induced Kinase Activation," seeks to unravel the molecular pathways underlying how cancer cells acquire the...
- The National Cancer Institute (NCI) awarded a $127,968 Project Grant under the Cancer Research Manpower (CFDA 93.398) federal grant program to The Leland Stanford Junior University (Stanford University) on December 24, 2024. The grant supports a research project titled "Investigating the Regulation of Cancer Cell Death by NFE2L1" with a planned completion date of August 31, 2026. The goal of this research is to better understand the molecular mechanisms of cancer cell resistance to...
The Leland Stanford Junior University (Stanford University) was awarded a $642,732 Project Grant from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393). The grant aims to develop and deploy novel single-cell technologies to unravel the genetic and phenotypic heterogeneity within endometrial carcinoma, a common but highly diverse form of uterine cancer. Specifically, the project will utilize the Genotyping in Fixed Transcriptomes (GIFT) approach to profile mutations and transcriptomes in individual cancer cells, including from archived FFPE tissue samples. This comprehensive single-cell analysis is expected to refine the molecular classification of endometrial cancer subtypes, improve prognostication, and inform personalized treatment strategies. The 5-year project is scheduled to commence on August 1, 2025.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $642.7k | 7/30/25 |