Project Grant R37CA302422
- This federal Project Grant award from the National Cancer Institute (CFDA 93.393 Cancer Cause and Prevention Research program) provides $651,859 to the Ann & Robert H Lurie Children's Hospital of Chicago to conduct the "#AYAOSM: An Influencer-Driven Social Media Intervention for Oral Chemotherapy Adherence" research project. The 5-year project aims to develop and evaluate a social media-based intervention to improve oral chemotherapy adherence among adolescents and young adults...
- This federal Project Grant award from the National Cancer Institute (CFDA 93.398 - Cancer Research Manpower) provides $185,693 to the Research Institute at Nationwide Children's Hospital to implement a digital health parent coaching intervention aimed at improving neurodevelopmental outcomes for young childhood cancer survivors in underserved communities. The project will be conducted over a 5-year period from March 1, 2025 to February 28, 2030. The Research Institute, a non-profit research...
- The University of Chicago was awarded a $361,807 federal Project Grant from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) to tailor an engaging technology-assisted cognitive behavioral therapy (TCBT) program for adolescents and young adults (AYAs) diagnosed with hematological malignancies. The grant will fund the refinement and tailoring of the existing "MYTH" TCBT intervention to create "MYTH-C" - a version specifically designed...
- The National Cancer Institute (NCI) awarded a $4,236,812 Project Grant under the Cancer Cause and Prevention Research federal grant program (CFDA 93.393) to Children's Hospital Los Angeles (CHLA). The grant, effective September 10, 2025 through August 31, 2029, will fund a study to evaluate the use of a patient navigation intervention to improve transition outcomes for young adult survivors of childhood cancer, particularly those from low socioeconomic status and underinsured/uninsured...
- This Project Grant award from the National Cancer Institute (CFDA 93.398 Cancer Research Manpower program) provides $319,505 to the Regents of the University of Michigan to build nationwide investigator capacity in methods for adapting and personalizing cancer control interventions. The project aims to address the growing demand for new methodological skills in developing adaptive interventions, which are evidence-based protocols that guide how individual information can be used to deliver...
- This $683,472 Project Grant awarded by the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) supports the development of a novel targeted therapy for acute myeloid leukemia (AML). The principal investigators at the University of Cincinnati are conducting preclinical research to evaluate a differentiation-inducing agent (HOSU-53) that targets the mitochondrial enzyme DHODH. The goal is to promote AML cell differentiation, activate the immune system, and induce ferroptosis to...
- This federal Project Grant award for $227,941, provided by the National Cancer Institute (CFDA 93.393 Cancer Cause and Prevention Research), will fund the development and piloting of the "Cancer Care Companion" - an electronic health record (EHR) tool to improve information exchange and self-management for pediatric cancer patients and their families. The project aims to engage parents and pediatric oncology clinicians to co-develop the EHR-based communication tool, which will adapt...
- The National Cancer Institute (NCI) awarded a Project Grant under CFDA 93.393 - Cancer Cause and Prevention Research to St. Jude Children's Research Hospital Inc. for the "Evaluation of Cardiovascular Health Outcomes among Survivors 2 (ECHOS-2)" study. The $772,418 grant, awarded on September 1, 2025, will test the efficacy of an eHealth-delivered intervention to improve adherence to cardiomyopathy screening among adult survivors of childhood cancer. The study aims to enroll 350...
- The National Cancer Institute (NCI), under the Cancer Biology Research federal grant program (CFDA 93.396), awarded a $530,106 Project Grant to the Children's Hospital Medical Center in Cincinnati, Ohio. The grant, awarded on September 11, 2025, supports research aimed at understanding and targeting polyamine metabolism in leukemia stem cells (LSCs) to improve outcomes for patients with acute myeloid leukemia (AML). The overarching goal is to develop LSC-directed therapies that can help overcome...
- This federal Project Grant award of $676,550 from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) supports research to understand the impact of socioeconomic status (SES) and adversity on hematopoietic cell transplant (HCT) outcomes in pediatric patients with high-risk hematological malignancies. The primary goals are to: 1) quantify the association between donor and recipient SES with pediatric HCT outcomes, and 2) evaluate how donor and recipient SES...
This federal Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) will fund a $717,786 study to evaluate the efficacy of a tailored medication adherence-promotion intervention called SUMMIT for adolescents and young adults (AYAs) with cancer. The study aims to improve medication adherence among AYAs, who often struggle with adherence, leading to poor health outcomes like relapse and death. The Children's Hospital Medical Center in Cincinnati, Ohio will conduct this randomized clinical trial over a 5-year period from September 2025 to August 2030. The project will recruit 160 AYAs receiving care from pediatric and adult hospitals and evaluate whether the personalized SUMMIT intervention results in greater improvements in electronically-monitored medication adherence compared to standard of care.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $717.8k | 8/27/25 |