Project Grant R35GM166295
- The National Institute of General Medical Sciences awarded Baylor College of Medicine $440,000 on February 13, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the physical principles governing nucleolar condensates and their role in ribosome biogenesis. The research develops quantitative microscopy methods to determine how nucleolar composition changes in response to cellular stimuli and during cellular transitions. The work tests the hypothesis...
- The National Institute of General Medical Sciences awarded Texas A&M University System Health Science Center $420,657 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859, assistance type Project Grant) to support research on nanoscale structure and dynamics within nuclear pores and condensates. The funded research examines intrinsically disordered proteins and regions in the proteome, with focus on transport properties of the nuclear pore complex and...
- The National Institute of General Medical Sciences awarded The University of Texas Health Science Center at San Antonio $378,000 on May 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate how intrinsically disordered proteins and regions regulate nuclear processes essential for genome stability, including transcription, RNA processing, and the DNA damage response. Over five years through April 30, 2031, the recipient will identify sequence and...
- The National Institute of General Medical Sciences awarded Baylor College of Medicine $1.92 million on June 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop technologies for detecting and annotating genomic features hidden within intergenic regions of prokaryotic genomes. The project runs through May 31, 2030, and is performed in Houston, Texas. Current genome annotation software misses small proteins due to size cutoffs and fails to detect non-coding...
- The National Institute of General Medical Sciences awarded $420,476 to the University of Texas Health Science Center at Houston on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support structural and mechanistic studies of eukaryotic gene transcription regulation. The recipient will conduct five years of integrated structural and molecular biology research investigating how the human CDK8 kinase module (comprising MED13, MED12, CDK8, and CYCC)...
- The National Institute of General Medical Sciences awarded Baylor College of Medicine $400,000 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the biochemical and structural principles underlying taxa-specific antibacterial activity in natural products. The research focuses on two model systems to answer how taxa-specific natural products inhibit novel bacterial targets and what chemical and mechanistic features differentiate...
- Federal Grant Award Summary Baylor College of Medicine received a $562,817 Project Grant award from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025, through July 1, 2026. The award funds the purchase and installation of a BD FACSDiscoverTM S8 Spectral and Imaging Cell Sorter for the institution's Cytometry and Cell Sorting Core. This instrument will support research conducted by eighteen...
- The National Institute of General Medical Sciences awarded the University of Texas at Dallas $431,750 on February 15, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support five-year research into the mechanisms regulating kinetics and specificity of nuclear-cytoplasmic transport. The research addresses how nuclear pore complexes (NPCs) vary in number, post-translational modifications, and protein composition across cellular and developmental contexts, and how...
- The National Institute of General Medical Sciences awarded The Wistar Institute of Anatomy and Biology $506,550 on March 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support research on compartmentalization and discrimination of double-stranded RNA in the nucleus. The funded research explores fundamental biological principles governing how cells distinguish self from non-self RNA molecules, specifically examining the balance between sensing pathogenic...
- The National Institute of General Medical Sciences awarded the Trustees of Boston University $433,750 on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop network-based computational models for understanding continuous cell states in human development and disease. Over five years through February 28, 2031, the research group will create methods to integrate multiple modalities of large-scale genomics data, with emphasis on epigenetics and the...
The National Institute of General Medical Sciences awarded Baylor College of Medicine $416,000 on July 20, 2026, under the Biomedical Research and Research Training program (CFDA 93.859, assistance type Project Grant) to investigate intrinsically disordered region-mediated interaction networks linking chromatin state to RNA export. The research addresses molecular mechanisms by which intrinsically disordered regions in RNA export factors ensure efficient export of highly transcribed genes, facilitate coordinated assembly of RNA export machinery, and promote selective localization of RNA export factors into subnuclear foci. The funded work employs advanced tools in structural biology, epigenomics, chemical biology, and microscopy, including rapid manipulation of involved activities in living cells and rigorous assays measuring outcomes through nascent RNA analysis, genomics, and live-cell microscopy. Performance occurs in Houston, Texas, with an ultimate completion date of April 30, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $416.0k | 7/20/26 |