Project Grant R35GM163606
- The National Institute of General Medical Sciences awarded The Johns Hopkins University $406,026 on March 5, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop biophysical models of biomolecular condensate dynamics. The work addresses the need for quantitative mathematical models to interpret experimental measurements of biomolecular condensates—non-membrane-bound organelles formed through phase separation that enable cellular functions including ribosomal...
- The National Institute of General Medical Sciences awarded the University of Maryland, College Park $405,390 on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859, Project Grant R35GM161807) to develop improved force fields for molecular simulations of cellular membranes and associated proteins. The research focuses on enhancing computational models of lipid interactions and peptide-lipid interactions by incorporating long-range dispersion interactions and...
- The National Institute of General Medical Sciences awarded The University of Chicago $480,083 on April 15, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate natural variation in embryo development across fly species, with performance through January 31, 2031, in Chicago, Illinois. The research compares developmental mechanisms across multiple Dipteran species to understand how embryonic gene networks evolve and acquire plasticity. The project...
- The National Institute of General Medical Sciences awarded the University of Maryland, Baltimore $427,625 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to fund research on the bioinorganic chemistry of zinc finger proteins and hydrogen sulfide reactivity. The research investigates how hydrogen sulfide, a gaseous signaling molecule, modifies cysteine residues in zinc finger proteins through persulfidation, converting thiols to persulfides and...
- The National Institute of General Medical Sciences awarded $410,473 to the Regents of the University of Michigan on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop quantitative theory and computational models of collective cellular response to complex biophysical cues. The research encompasses two projects: investigation of swarming bacterial colonies' response to intestinal tissue cues in healthy and disease states, and analysis of...
- The National Institute of General Medical Sciences awarded $419,296 to the University of Maryland, College Park on July 10, 2026 under the Biomedical Research and Research Training program (CFDA 93.859) to conduct research on genome regulatory mechanisms mediating abscisic acid stress hormone response and stomatal aperture control in plants. The research program investigates how plants coordinate gene and genome activity in response to environmental stress, focusing on drought adaptation. The...
- The National Institute of General Medical Sciences awarded the University of Massachusetts Boston $425,333 on March 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support research on cellular and molecular mechanisms of stem and progenitor cell development during tissue homeostasis and after injury. The research uses the Drosophila melanogaster blood system as a model to examine how multiple cell types within stem and progenitor cell niches use inflammatory...
- The National Institute of General Medical Sciences, a component of the Department of Health and Human Services National Institutes of Health, awarded The Johns Hopkins University $420,936 for a Project Grant (CFDA 93.859, Biomedical Research and Research Training) on April 1, 2026. The award funds research investigating mechanisms of protein self-assembly coupled to membrane mechanics in clathrin-mediated endocytosis. The research addresses how cargo controls the nucleation and growth of...
- The National Institute of General Medical Sciences awarded Worcester Polytechnic Institute $554,599 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to conduct research on how neuropeptides and monoamines establish sex-specific behavioral responses in the nematode Caenorhabditis elegans. The project will define the mechanisms by which NLP-3 neuropeptides and serotonin modulate a shared neural circuit to create sex-divergent avoidance behavior in...
- The National Institute of General Medical Sciences awarded the University of Maryland, Baltimore $498,000 on September 22, 2025, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate molecular mechanisms of endocytosis of the activated B cell receptor in health and disease. The research elucidates a novel hybrid endocytosis mechanism in B cells that internalizes large antigens. The investigator identified clathrin-associated smooth raised membrane (CSRM)...
The National Institute of General Medical Sciences awarded the University of Maryland Baltimore County $416,456 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support basic research into the genetic and endocrine regulation of multi-organ plasticity and sexually dimorphic behaviors. The research investigates how hormones coordinate physiological responses across multiple organ systems in response to environmental change, with particular focus on the sesquiterpenoid juvenile hormone in Drosophila flies and its role in regulating maturation of reproductive and non-reproductive behaviors in a sex-specific manner. The work examines mechanisms by which sensory information reaches neurosecretory cells and how feedback from target tissues regulates hormone release dynamics for systemic physiological and behavioral changes. Performance occurs at Baltimore, Maryland, with a period of performance extending through May 31, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $416.5k | 7/31/26 |