Project Grant R35GM160216
- The University of California, Davis received a $435,769 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). This 5-year grant, awarded on September 1, 2025, supports the university's research efforts to uncover the physical principles that define the function of the cellular glycocalyx. The key objectives are to develop novel imaging tools, computational models, and genetic engineering...
- This $381,801 project grant award from the National Institute of General Medical Sciences (CFDA 93.859 Biomedical Research and Research Training) will fund research at the University of California, Santa Cruz to gain insights into how biological timers control development and how the apical extracellular matrix is constructed and remodeled in the nematode model organism C. elegans. The research aims to understand the properties, components, and regulation of developmental timers that synchronize...
- This federal Project Grant award of $249,000.00 was made on September 1, 2025 under the Biomedical Research and Research Training program (CFDA 93.859), administered by the National Institute of General Medical Sciences (NIGMS). The grant supports research aimed at determining how biophysical cues, such as matrix viscoelasticity, shape the behavior and interactions of macrophages and T-cells within the tumor microenvironment. The University of California, San Diego (UCSD) is the awardee, with...
- This Project Grant award of $501,000.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research by The Regents of the University of California, San Francisco (UCSF) to develop simulation-based models that can more accurately interpret experimental data in structural biology. The goal is to enhance understanding of how macromolecules communicate and interact, which is vital for advancing...
- The University of California, Merced received a $550,108 Project Grant award under the National Institute of General Medical Sciences' (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) to conduct fundamental research on the genetic regulation of microbial community formation, with a focus on biofilms. The project, which runs from May 5, 2025 to March 31, 2030, aims to provide new insights into the molecular and mechanistic bases of biofilm development, regulation, and...
- The University of California, Merced received a $200,000 Project Grant award from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation on May 15, 2022 to support research under the Engineering program (CFDA 47.041). The award will fund research from May 15, 2022 through April 30, 2024 to develop multi-scale models of cell-matrix mechanical interactions during endothelial cell network assembly. The Engineering program seeks to improve quality of life and...
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $400,530 Project Grant to the Rector & Visitors of the University of Virginia (UVA) on June 1, 2025. The grant supports UVA's research to develop next-generation nanodisc tools that can characterize membrane protein-lipid interactions essential for understanding cell-cell interactions and communication. Specifically, the research will focus on...
- The National Institute of General Medical Sciences (NIGMS) awarded a $367,105 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to the University of Wisconsin - Madison to support research on regional extracellular matrix (ECM) remodeling. The research program aims to increase the rigor and reproducibility of approaches for capturing ECM heterogeneity and its influence on tissue load-bearing function. Key focus areas include developing improved methods for visualizing ECM...
- This Project Grant award was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The $437,709 award supports research to better understand the biophysical mechanisms underlying the generation of inward and outward curvature in cellular membranes. This research aims to elucidate the role of lipid bilayer interactions with the cytoskeleton and extracellular glycocalyx in controlling membrane bending...
- The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $139,341 project grant to the Regents of the University of California, San Francisco (UCSF) under the NSF Biological Sciences program (CFDA 47.074). The 3-year grant, effective August 1, 2023, supports collaborative research to investigate the biomechanical mechanisms underlying wound resilience in the single-celled organism Stentor coeruleus. The research will leverage cell biology, microfluidics, and...
The University of California, Santa Barbara was awarded a $415,662 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant, awarded on August 1, 2025, aims to explore the fundamental role of matrix-bound nanovesicles (MBVs) in extracellular matrix formation and wound repair. The research will utilize 3D collagen biomaterials and human mesenchymal stem cells to study the localization of MBVs within the extracellular matrix and determine if MBV production impacts a cell's ability to form an extracellular matrix. Additionally, the project will isolate MBVs from various cell types and examine their cargo and role in stem cell differentiation to understand how MBV cell origin influences tissue-specific wound repair. The grant is scheduled for completion by July 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $415.7k | 7/31/25 |