Project Grant R35GM160135
- The University of Arkansas, Fayetteville Division, is the recipient of a $436,326 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The project, titled "DISSECTING CRYPTIC GENETIC VARIATION UNDERLYING COMPLEX TRAITS IN DROSOPHILA", aims to use the Drosophila model organism to reveal cryptic genetic variation and uncover novel gene-gene and gene-environment interactions...
- This federal Project Grant award of $423,750.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant, awarded on May 1, 2025, supports a research project at New York University (NYU) School of Medicine to develop new conceptual and statistical approaches that integrate molecular, cellular, and population genetics to better understand the genetic basis of complex human traits and diseases....
- This federal Project Grant award of $227,435, awarded on August 1, 2025 by the National Institute of General Medical Sciences (NIGMS), provides funding for research on "Genetic Constraints on Adaptive Evolution" under the Biomedical Research and Research Training program (CFDA 93.859). The goal of the research program is to unravel how genetic constraints limit adaptation and how these constraints diverge between species. The University of Rochester, the awardee, will build on their...
- This federal Project Grant award of $395,000 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) will fund research on the phenotypic and adaptive consequences of chromosomal rearrangements in three insect systems: Timema stick insects, Callosobruchus maculatus seed beetles, and Lycaeides butterflies. The research aims to investigate how common different types of structural variants, such as deletions,...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $413,300.00 to the University of Southern California (USC) to conduct research in three critical areas of human genetics. The funded research will: Model recessive selection on complex traits by leveraging X chromosome data to better understand the strength of selection across different traits and diseases. Explore...
- The National Institute of General Medical Sciences (NIGMS) awarded a 5-year, $616,786 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The Regents of the University of California, San Francisco (UCSF) to conduct research aimed at uncovering how evolutionary forces shape patterns of genetic variation and drive phenotypic variation across human populations. The research focuses on three key areas: 1) exploring the effects of recessive deleterious alleles...
- This $380,406 federal Project Grant award, issued by the National Institute of General Medical Sciences (CFDA 93.859 - Biomedical Research and Research Training program), will support a 5-year research project at the University of Arizona investigating the evolutionary effects of emerging diseases on host populations. The project will leverage natural experiments in the Galapagos Islands to study how avian host species, such as Darwin's finches and Galapagos mockingbirds, adapt to novel...
- This federal Project Grant award of $393,093, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports a research project titled "Uncovering Spatio-Temporal, Mechano-Transcriptomic Signatures of Development". The principal investigator is Bianca Dumitrascu. The goal of this 5-year project is to understand the interplay between gene expression, cell morphology, and tissue-level mechanics in...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports research to investigate the mechanobiology of multicellular morphogenesis. The $365,077 award to the University of Arkansas, Fayetteville, aims to measure the distribution of intercellular mechanical forces during morphogenetic processes, such as branch elongation/retraction and bifurcation/budding, and connect these...
- This federal Project Grant award of $1,968,575.00 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), is focused on developing computational approaches and machine learning methods to predict DNA-binding specificities for transcription factor proteins and the functional effects of genetic variants within proteins. The overarching goal is to gain a predictive understanding of proteins, their interactions,...
This federal Project Grant award of $258,986 from the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training program supports research to unravel the genetic basis of complex trait variation and novel trait evolution. The primary focus is to explore cryptic genetic variations that are revealed through environmental perturbations, and to investigate genomic signatures in natural populations that have adapted to extreme environments. Key elements include employing a powerful mapping strategy, leveraging multi-omic analysis, and constructing gene-transcript-metabolite-phenotype networks to understand how these genetic variations influence complex traits. The award will fund this 5-year research project at the University of Arkansas, Fayetteville.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $259.0k | 8/20/25 |