Project Grant R35GM159880
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $423,616 Project Grant to Brown University. The grant, effective from September 1, 2025 to June 30, 2030, will support the development of integrative computational models to decode disease mechanisms and predict drug synergies in spatial transcriptomics. The research aims to uncover how the spatial arrangement of cells within tissues (cellular spatial...
- The U.S. Department of Health and Human Services, National Institute of General Medical Sciences (NIGMS) awarded a $449,625 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Trustees of Boston University. The grant, awarded on September 15, 2025, supports research to develop new experimental strategies and computational approaches for studying single-cell gene expression trajectories. The overarching goal is to enable foundational advances in...
- This federal Project Grant award of $436,001 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to create a novel spatial transcriptomics platform that increases accessibility and efficiency. The key products and services to be delivered include: Developing a spatial transcriptomics platform using a simple filter array format that increases sequencing depth per spatial barcode, enabling more data per...
- The National Institute of General Medical Sciences (NIGMS) awarded a $349,243 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Imagen Bioworks Inc. on September 12, 2025. The grant supports the development of an innovative "Spotlight-Omics" workflow that can cost-effectively isolate disease-relevant spatiotemporal phenotypes from live cell cultures for subsequent omics analysis. This workflow aims to address a critical limitation of current...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $421,999 in funding to Emory University from July 1, 2025 through April 30, 2030. The award supports research to investigate how posttranscriptional mechanisms, such as local RNA, direct centrosome activity and function. The research aims to determine the basis for cell cycle-dependent oscillations in RNA...
- This federal Project Grant award of $437,250.00 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), will fund a 5-year research project at the University of Pittsburgh focused on advanced computational approaches for integrating single-cell multi-omics data. The key objectives of this project are to: 1) Develop novel integration methods for combining single-cell RNA-seq, ATAC-seq, and cytometry data to...
- This $445,000 Project Grant award, funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports a research project focused on leveraging long-read transcriptomics to elucidate transcriptome complexity and advance genomic medicine. The central objective is to harness the power of long-read RNA sequencing to provide unprecedented insights into alternative splicing and its impact on gene products, which is...
- This federal Project Grant award of $393,093, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports a research project titled "Uncovering Spatio-Temporal, Mechano-Transcriptomic Signatures of Development". The principal investigator is Bianca Dumitrascu. The goal of this 5-year project is to understand the interplay between gene expression, cell morphology, and tissue-level mechanics in...
- The National Institute of General Medical Sciences (NIGMS) has awarded a $536,250 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the Sanford Burnham Prebys Medical Discovery Institute (SBP). The project aims to develop computational methods that can analyze single-cell transcriptomic data to better identify and study rare cell populations, such as tissue stem cells, senescent cells, and tumor-initiating cells. The approach will use...
- This federal Project Grant award, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports advanced quantitative analyses of long-read RNA sequencing data at both the bulk and single-cell levels. The $424,264 award, effective June 1, 2025 through May 31, 2030, will enable the University of Michigan to build upon their expertise in long-read sequencing bioinformatics and deliver new insights into...
The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), has awarded a $384,722 Project Grant to Emory University to develop statistical approaches for integrating multi-view, multi-section, and multi-sample spatial transcriptomics data to decipher disease mechanisms. The project aims to provide researchers with analytical tools to tackle challenges in population-scale spatial transcriptomics data analysis, beginning with multi-view analysis, progressing to multi-section integration, and ultimately achieving cohort-scale analysis. The project period runs from Sep 1, 2025 to Jun 30, 2030. This grant leverages Emory University's expertise in statistical genomics, biomedical research, and advanced data integration techniques to advance the field of spatial transcriptomics and its applications in understanding disease processes.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $384.7k | 8/27/25 |