Project Grant R35GM157121
- This $373,344 federal Project Grant award from the National Science Foundation's (NSF) Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), supports a collaborative research project led by Professors Julie Biteen of the University of Michigan and David Masiello of the University of Washington. The project aims to develop a multifunctional, high-sensitivity instrument to measure plasmon-enhanced chirality and enable the sensing of subtle, heterogeneous...
- This $126,656 Project Grant award, funded by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049), supports a collaborative research effort led by Professors Julie Biteen of the University of Michigan and David Masiello of the University of Washington. The goal is to develop a multifunctional, high-sensitivity instrument to measure plasmon-enhanced chirality and enable sensing of subtle, heterogeneous changes in chirality at the single-molecule...
- The National Science Foundation awarded a $238,688 Project Grant to the Missouri University of Science and Technology under the Engineering program (CFDA 47.041) to develop a new type of biomolecule sensing platform enhanced by infrared chiral metasurfaces. The university will design and analyze various mid-infrared chiral metasurfaces with high circular dichroism for biomolecule sensing. Nanofabrication processes will be developed to fabricate the chiral metasurfaces and integrate...
- This $388,983 federal Project Grant award from the National Science Foundation (NSF) Division of Chemistry's Chemical Measurement & Imaging Program and Chemistry of Life Processes Program supports the development of a new optical microscope by Professor Eric Potma at the University of California, Irvine. The instrument leverages chiral sum-frequency generation (SFG) microscopy to visualize protein structures in cells and tissues without the need for chemical labeling. This label-free imaging...
- This $450,000 Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports the development of a new spectroscopic tool called Chiroptical Second-Harmonic Light Scattering on Nanostructured Particles (CHIRON). The primary awardee, the Regents of the University of Michigan, will collaborate with researchers from the University of Bath to create this label-free, high-throughput analytical method for detecting and analyzing large biological structures...
- This $466,936 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports two research programs at the University of Illinois. The first program aims to create a library of stereodefined, functionalized, three-dimensional building blocks that can be used as "plugins" to optimize and diversify small molecule drug candidates. The second program seeks to develop a modular,...
- This $1,977,264 federal Project Grant, awarded by the U.S. Department of Health and Human Services' National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop a novel multimodal imaging platform that combines fluorescence super-resolution and tomographic polarized light imaging. The project will create open-source computational imaging tools to recover the dielectric tensor in multiple scattering samples using...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $1,000,000 to the Trustees of the Colorado School of Mines will develop an advanced mid-infrared imaging instrument to analyze the interactions of chiral drugs with biological tissues. The project aims to provide detailed spatial information on how chiral drug molecules behave in different tissue environments, which is crucial for developing safer and more effective medications....
- The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $639,361 Project Grant to The Washington University to investigate the effects of nanomaterial chirality on immune cells and innate immunity from June 15, 2021 to May 31, 2026. This award will fund research under the NSF Engineering program (CFDA #47.041) to study how the handedness of nanoparticles, also known as chirality, impacts immune cell function and the body's innate...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $330,076 to Trestle Optics LLC, a small disadvantaged business located in Irvine, California. The award supports the development of a novel photothermal microscopy platform integrated with spatial light interference imaging. This innovative instrument is designed to enable non-destructive profiling and mapping of...
This $396,500 Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop cutting-edge nanophotonic technologies for probing and manipulating molecular and cellular chirality. The research seeks to provide groundbreaking insights into the interplay between molecular and cellular chirality, and how they affect cellular functions and disease mechanisms. Key anticipated outcomes include novel diagnostic tools, safer chiral drugs, and non-invasive treatment methods, which could significantly advance chirality research and bridge the divide between molecular and cellular understanding. The award was granted to the University of Illinois, a prominent public research university with extensive experience in federal contracting and grant work across multiple scientific domains.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $396.5k | 8/7/25 |