The National Institute of General Medical Sciences (NIGMS) awarded Wayne State University a 5-year, $373,129 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to investigate mechanisms of mitophagy, a cellular process that degrades damaged mitochondria. The research aims to generate novel genetic tools and leverage the fruit fly model organism to elucidate how different forms of mitophagy contribute to tissue health and homeostasis. Findings from this work are expected to provide foundational knowledge that can facilitate the development of mitophagy-targeting therapeutics for conditions like Parkinson's disease, diabetes, and ischemia-reperfusion injuries. The project will be conducted by Wayne State's research team in Detroit.
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