Project Grant R25MH144979
Award Date 8/18/26
Completion Date 5/31/31
Dollars Obligated $215K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Philadelphia, PA 19104, USA
Similar Awards
- The National Institute of Mental Health awarded the Regents of the University of Michigan $215,998 on August 19, 2026, under the Mental Health Research Grants program (CFDA 93.242) to deliver the Advancing Research Careers in HIV Program, a two-year research education and mentoring initiative. The program cultivates the next generation of interdisciplinary HIV social and behavioral science researchers by educating and guiding master's-level students in public health, nursing, and social work...
- The National Institute of Mental Health awarded Drexel University $100,228 on December 16, 2026, under the Mental Health Research Grants program (CFDA 93.242) to support research on HIV-induced trained immunity in microglia and its contribution to HIV-associated neurocognitive disorders (HAND). The project investigates whether trained immunity—a form of innate immune memory characterized by hyperresponsiveness to secondary inflammatory stimulation—occurs in microglial cells of people living with...
- The National Institute of Mental Health awarded The Trustees of The University of Pennsylvania $1,217,055 on July 17, 2026, under the Mental Health Research Grants program (CFDA 93.242) to investigate selective inhibition of T cell trafficking to the brain during acute SHIV infection in rhesus macaques. The research leverages a validated nonhuman primate model of HIV neuropathogenesis and persistence to determine how blocking T cell circulation during acute SHIV.D infection affects the...
- Federal Project Grant Award Summary The University of Pennsylvania received a $457,596 Project Grant from the National Institute of Mental Health under the Mental Health Research Grants program (CFDA 93.242), awarded August 1, 2025, with completion targeted for July 31, 2027. This research initiative will deliver a comprehensive analysis identifying key engagement characteristics that enhance the effectiveness of digital health interventions (DHIs) for HIV prevention and care among at-risk...
- The National Institute on Drug Abuse, a component of the National Institutes of Health, awarded the University of Pennsylvania $500,000 on May 18, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and test multimodal artificial intelligence and machine learning models that integrate structured and unstructured electronic health record data, claims, pharmacy records, genomics data, and imaging data to enhance personalized clinical decision support and address unmet...
- The National Institute of Mental Health awarded $812,484 to The Trustees of the University of Pennsylvania on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to test the effectiveness and dissemination of a digital intervention promoting home HIV testing and linkage to PrEP among men who have sex with men in Philadelphia. The project will randomize approximately 1,000 MSM participants to an experimental arm receiving tailored social-media and SMS messages...
- The National Institute of Mental Health awarded The Trustees of The University of Pennsylvania $200,538 on December 14, 2025, under the Mental Health Research Grants program (CFDA 93.242) to investigate functional cortical development and its relationship to transdiagnostic psychopathology risk. The recipient will map the functional organization of the cortex across development using a normative modeling framework applied to four large-scale developmental datasets: the Philadelphia...
- The National Institute of Mental Health awarded The Johns Hopkins University $149,190 on August 2, 2026, under the Mental Health Research Grants program (CFDA 93.242) to identify intervention opportunities in the continuum of cognitive impairment among persons aging with HIV. The research will estimate the proportion of cognitive impairment cases among people with HIV potentially attributable to psychosocial and behavioral risk factors, prioritizing those interventions that could prevent the...
- The National Institute of Mental Health awarded Thomas Jefferson University $431,750 on May 15, 2026, under the Mental Health Research Grants program (CFDA 93.242) to characterize the role of DNA-dependent protein kinase (DNA-PK) in HIV latency and transcription within central nervous system microglial cells, the primary CNS reservoir for HIV. The research aims to define the molecular mechanisms by which DNA-PK supports HIV transcription in microglial cells and to test the hypothesis that DNA-PK...
- The National Institute of Mental Health awarded the University of California, Los Angeles $787,498 under the Mental Health Research Grants program (CFDA 93.242) on July 1, 2026, to characterize HIV persistence and neuroinflammation in central nervous system (CNS) reservoirs in vivo using barcoded HIV tracking, spatial transcriptomics, single-cell RNA sequencing, and integration site analysis. The research investigates the contributions of T cell populations in HIV persistence and inflammation...