Project Grant R24AI201148
- The National Institute of Allergy and Infectious Diseases awarded the University of Alabama at Birmingham $1,173,450 on September 18, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the structure-function relationships of influenza non-structural protein 1 (NS1) and nuclear export protein (NEP) that govern the influenza virus lifecycle. The research will define mechanistic and structural understanding of how NS1 and NEP accomplish their viral...
- The National Institute of Allergy and Infectious Diseases awarded the University of Alabama at Birmingham $490,611 on April 3, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the role of regulatory dendritic cells in neonatal immune responses to influenza infection. The research examines how a newly identified form of dendritic cell maturation (mREGDC1) impairs protective CD8 T cell responses in newborns and young infants during respiratory viral...
- The National Institute of Allergy and Infectious Diseases awarded the University of Alabama at Birmingham $512,842 on July 13, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate how capsule O-acetyltransferases modulate pneumococcal fitness and contribute to bacterial virulence. The research focuses on characterizing the function of capsule polysaccharide O-acetyltransferase enzyme families in Streptococcus pneumoniae and their role in coordinating with...
- The National Institute of Allergy and Infectious Diseases awarded the University of Texas Medical Branch at Galveston $807,498 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to maintain and operate a comprehensive reference center for emerging viruses and arboviruses. The award supports four specific aims: maintaining a comprehensive collection of emerging viruses, arboviruses, and associated reagents including antisera, antigens, and cDNA clones...
- The National Institute of Allergy and Infectious Diseases awarded The University of Alabama in Huntsville $747,400 on August 18, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop small molecule inhibitors of non-structural protein 2 (NSP2) protease as therapeutics against Venezuelan equine encephalitis virus. The research advances lead candidate compounds through structure-activity relationship studies guided by NSP2 inhibition assays, in vitro antiviral...
- The National Institute of Allergy and Infectious Diseases awarded the University of Alabama at Birmingham $480,853 on August 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855, Project Grant R01AI195802) to investigate the stability and dynamics of the human anti-carbohydrate antibody repertoire across the lifespan. The research examines how chronic exposure to commensal microbiota-derived glycan determinants shapes the anti-carbohydrate (AC) B cell repertoire....
- Federal Grant Award Summary The University of Alabama at Birmingham received a $148,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 1, 2025, with a completion date of July 31, 2027. This research project investigates the role of calcium ions (Ca2+) in the assembly of the exosporium of Bacillus anthracis, the bacterium responsible for anthrax. The research focuses on...
- The National Institute of Allergy and Infectious Diseases awarded the University of California Irvine $141,712 on February 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to characterize a novel histidine phosphotransfer system involved in the virulence of Mycobacterium tuberculosis. The funded research investigates how virulence-associated dikinase (VADK) coordinates metabolism and virulence in MTB by interacting with partner proteins. The work combines...
- The National Institute of Allergy and Infectious Diseases awarded the University of Alabama at Birmingham $172,220 on November 3, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support structural and mechanistic research into HIV-1 Rev nucleocytoplasmic trafficking as a potential target for novel antiretroviral drug development. The research investigates how the HIV-1 Rev protein, which mediates nuclear export of viral messenger RNA necessary for virus...
- The National Institute of Allergy and Infectious Diseases awarded The University of Akron $538,741 on August 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct structure and function studies of orphan cytochrome P450 enzymes CYP126A1 and CYP143A1 from Mycobacterium tuberculosis. The research will employ resonance Raman spectroscopy and biochemical analysis to define the structural features of reactive intermediates governing CYP126A1 catalysis, elucidate...
The National Institute of Allergy and Infectious Diseases awarded the University of Alabama at Birmingham $744,991 on August 1, 2026, to develop a community knowledgebase supporting virus taxonomy research under the Allergy and Infectious Diseases Research program (CFDA 93.855). The funded work centers on creating a taxonomic database, website, and supporting tools focused on virus classification and nomenclature maintained by the International Committee on Taxonomy of Viruses (ICTV). The deliverables include expanded availability and breadth of taxonomic and virological information; tools for searching and displaying virus taxonomy data; and strengthened connections between the ICTV and stakeholders across scientific, veterinary, medical, educational, and regulatory communities. The project runs through July 31, 2031, with place of performance in Birmingham, Alabama. The award is structured as a Project Grant, a standard assistance mechanism under the NIAID program designed to support biomedical research and research training in infectious diseases and related areas at nonprofit institutions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $745.0k | 7/27/26 |