Project Grant R21NS151067
- The National Institute of Neurological Disorders and Stroke awarded The Regents of the University of Colorado (University of Colorado-Denver) $115,265 on November 27, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating how developmental glutamatergic signaling modulates oligodendrocyte differentiation in the early brain. The recipient will use designer receptors exclusively activated by...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded The Medical University of South Carolina $100,228 on December 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research on complement-mediated mechanisms of injury and repair in germinal matrix hemorrhage, a leading neurological injury of prematurity....
- The National Institute of Neurological Disorders and Stroke awarded The Regents Of The University Of Colorado, doing business as University Of Colorado-Denver, $269,998 on June 10, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds NEUROASCENT, a career enhancement and neuroscience training program designed to support neuroscience-focused PhD students across multiple graduate programs at CU Anschutz. The program...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded $153,560 to the Broad Institute, Inc. (doing business as Broad Institute of MIT and Harvard) on December 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research examining how excitatory neurons regulate interneuron fate, position, and survival during...
- The National Institute of Neurological Disorders and Stroke awarded The Regents of the University of Colorado (doing business as University of Colorado-Denver) $535,124 on June 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to conduct research on neural circuits for disinhibition in the cerebellum. The funded work uses functional recordings, circuit-targeted activity manipulations, and behavioral analysis to determine how...
- The National Institute of Neurological Disorders and Stroke awarded $152,300 to The Regents of The University of Colorado (University of Colorado-Denver) on May 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to conduct research on the role of microglia in developmental myelination. The research investigates how microglial cells target and remove myelin sheaths during normal brain development to refine the amount and placement...
- The National Institute of Neurological Disorders and Stroke awarded The Trustees of Columbia University in the City of New York $126,900 on March 7, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research to exploit RNA biogenesis, specifically alternative splicing programs, to accelerate maturation of human neurons in vitro and to develop models of age-related tauopathies. The research addresses a fundamental...
- The National Institute of Neurological Disorders and Stroke awarded $622,687 to the University of Colorado-Denver on August 19, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the synaptic basis of temporal learning in the cerebellum. The research examines how synaptic diversity in the cerebellum sculpts granule cell temporal basis sets to enable precise sensory-motor transformations underlying motor behaviors. The...
- The National Institute of Neurological Disorders and Stroke, a component of the Department of Health and Human Services National Institutes of Health, awarded $575,655 to the Regents of the University of Colorado (doing business as University of Colorado-Denver) on June 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) for a Project Grant (R01NS143960). The award funds research investigating whether paired vagus nerve...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, awarded Drexel University $547,255 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds investigation of the functional organization of descending neuron networks that control collision-avoidance behavior. Using electron microscopy connectomes of the central nervous system at synaptic...
The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services, awarded $429,000 to The Regents of the University of Colorado, doing business as University of Colorado-Denver, on September 2, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, Program Grant R21NS151067). The award funds research on transcriptional and epigenetic regulation of neural progenitor fates during vertebrate brain development. The research uses single-cell multiome time-course analysis to identify how ectodermal cells interpret mesoderm-derived signals and secreted-factor gradients during gastrulation to produce distinct neural progenitor populations. The project provides comprehensive molecular profiles of cells undergoing activation-transformation in zebrafish, resolving neural progenitors from neural crest, placodal, and epidermal progenitors and identifying transcriptionally distinct progenitor populations in the developing hindbrain that correlate with later-stage cell types forming different hindbrain structures. Work is performed in Aurora, Colorado. The period of performance runs from September 2, 2026, through August 31, 2027. The NINDS Extramural Research Programs support fundamental research on brain structure and function and research addressing neurological disease, evaluated on scientific merit, technical adequacy, investigator competency, facility adequacy, budget justification, and program relevance through technical peer review panels and the National Advisory Neurological Disorders and Stroke Council.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $429.0k | 9/2/26 |