Project Grant R21NS142808
Award Date
4/1/25
Completion Date
3/31/27
Dollars Obligated
$217K
Federal Agency
National Institute of Neurological Disorders and Stroke
Awardee
Emory University (S352L5PJLMP8)
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
Georgia, USA
Similar Awards
This $667,235 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to identify genetic and epigenetic factors influencing stroke and recurrent stroke risk in a multiethnic population. The primary awardee, the University of Virginia, will leverage data from the REGARDS and VISP studies to perform epigenome-wide association...
The federal Project Grant award R01NS131554, "DYNAMIC CEREBROVASCULAR MORPHOLOGY CHANGES IN ACUTE ISCHEMIC STROKE", is funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $1,867,817 grant aims to investigate dynamic changes in cerebrovascular morphology after acute ischemic stroke and use cerebrovascular features to improve stroke outcome...
This $1,199,991 Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program aims to develop novel technologies for real-time assessment of blood clot properties to improve stroke treatment. The key products and services under this grant include:
Integration of a sub-millimeter Raman fiber probe into a catheter for intravascular, in-vivo measurement of clot chemical composition.
Training of a convolutional neural network to...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) provides $458,005 to Yale University to conduct transcriptomic analysis of stroke thrombi and blood samples.
The goal is to identify differences in the cellular pathogenesis of stroke thrombi caused by atherothrombosis versus cardioembolism. The research aims to determine whether thrombi of...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), provides $776,503 to The General Hospital Corporation (Massachusetts General Hospital) to investigate the role of perivascular inflammation and vascular remodeling in cerebral small vessel diseases (CSVD), which can lead to intracerebral hemorrhage. The project will leverage autopsy cases and...
This federal Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a Fused Imaging and Large Language Foundational Model (FILLM) to enhance the prediction of 90-day outcomes for acute ischemic stroke patients. The $124,485 award will enable the development and testing of the FILLM model, which integrates unstructured...
This $539,597 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program aims to address the paradox of poor outcomes despite successful recanalization in stroke patients treated with endovascular stroke therapy (EVT). The project seeks to:
Create a longitudinal clinical and imaging dataset to evaluate the role of final infarct volume on outcomes for...
This Project Grant award in the amount of $1,023,404 from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research to investigate the role of cerebrovascular O-GlcNAcylation in predisposing diabetics to stroke, worsening stroke-induced neurovascular injury, and impairing functional recovery after stroke. The award, granted to the University of South Carolina and effective from September 26, 2024 to August 31, 2025, will fund in vitro...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), supports research to investigate the role of the skull bone marrow niche in post-stroke inflammation and recovery. The $798,848 award, running from March 1, 2025 to February 28, 2029, will fund research to examine the information transfer between the central nervous system and the skull...
This federal Project Grant award, valued at $853,135.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to define the role of complement C3A receptor signaling in exacerbating acute post-ischemic brain injury and long-term neurological dysfunction following stroke. The research aims to demonstrate that inhibiting...