Project Grant R21NS142543
- This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $478,732 to Seattle Children's Hospital to characterize the cellular and molecular features of human cerebellar progenitor zones. The research leverages expertise in human cerebellar development and access to fetal tissue to conduct in vitro assays, live imaging, and...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services, awarded a $4,528,840 Project Grant to The Salk Institute For Biological Studies under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The three-year award beginning August 19, 2022 will fund research to functionally dissect cerebellar output circuits that orchestrate limb motor control. Specifically, the grantee will...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $676,388 to St. Jude Children's Research Hospital Inc. to conduct research on how polarity signals coordinate neuronal differentiation and nuclear organization. The key aims of the research are to define how the proteins SIAH2 and PARD6A regulate chromatin compaction and nuclear...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on August 1, 2025 for $1,180,687. The purpose of this 8-year project is to investigate how neural stem cell niches transition from embryonic to postnatal stages in the human forebrain, with a focus on characterizing the different neural...
- This federal Project Grant award of $1,208,677.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research conducted by President and Fellows of Harvard College, doing business as Harvard Medical School, over an 8-year period from August 2025 to July 2033. The primary goal of this research is to answer the question: How do the...
- This federal Project Grant award, valued at $147,486, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The purpose of this award is to investigate the function of a ciliary protein in neural development, with a focus on uncovering novel molecular mechanisms involved in synapse formation that may be relevant to neurological disorders. Using C. elegans as...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,270,237 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the Icahn School of Medicine at Mount Sinai. The 5-year grant, effective August 1, 2025, will support a program to investigate the pathogenic mechanisms associated with neural disease in Congenital Disorders of Glycosylation (CDG). The program will utilize zebrafish, Drosophila, and human...
- This Project Grant award of $637,820 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support research to identify novel genes responsible for proper cortical development, lamination, and axonal trajectories, as well as genes controlling the internal capsule and corticospinal tract in mice. The research will leverage forward genetics in mice to uncover new fundamental...
- This federal Project Grant award of $115,327.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports research to investigate the protracted maturation of cortical inhibitory neurons (CINs) in the human brain and their contribution to regional cortical specification and vulnerability during the perinatal period. The research aims to...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $125,724 project grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on January 23, 2025. The project, titled "Hypoxia-Induced Misdirection: Understanding Postnatal Inhibitory Interneuron Migration in Neonatal Hypoxic Injury", aims to use computational approaches to identify altered...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $516,175 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Seattle Children's Hospital, doing business as Seattle Children's Research Institute. The 2-year grant, with an award date of August 1, 2025, will fund research to elucidate the developmental processes and mechanisms driving the expansion of cerebellar progenitor zones in ferrets, which exhibit similarities to human brain development. The project aims to characterize primary and secondary cerebellar progenitor zones in ferrets throughout development using immunohistochemical and in situ hybridization assays, as well as single-cell/nucleus multi-omics approaches. The goal is to gain insights into human cerebellar development and implications for modeling neurological disorders.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $516.2k | 7/28/25 |