Project Grant R21NS140909
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Wisconsin–Madison a $629,031 Project Grant effective June 1, 2025, through February 28, 2030, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This research initiative will develop and validate Optical Cell State Imaging (OCSI), a label-free, live-cell classification technology designed to distinguish...
- Federal Project Grant Award Summary The University of Wisconsin–Madison received a $434,769 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), with an award date of June 27, 2025, and ultimate completion date of March 31, 2030. The research project investigates the regulation of invadosome-mediated peripheral axon guidance by ErbB signaling,...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $149,294 to the University of Wisconsin–Madison on July 4, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports a one-year research project (concluding June 30, 2026) investigating the mechanisms of ZIC2 function in zebrafish to advance understanding of holoprosencephaly (HPE), a congenital malformation...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Wisconsin–Madison a Project Grant totaling $494,240 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective February 16, 2026, through January 31, 2031. This award funds a five-year research investigation into microRNA (miRNA) degradation mechanisms in post-stroke brain tissue, specifically examining...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $414,305 to the University of Wisconsin-Madison under its Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) effective August 1, 2025, with a completion date of July 31, 2027. This project grant funds fundamental neuroscience research aimed at identifying molecular mechanisms underlying epileptogenesis—the progressive development of spontaneous...
- Federal Project Grant Award Summary The University of Washington received a $147,486 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective June 27, 2025, with a completion date of May 15, 2028. The award supports doctoral-level research investigating the function of a previously uncharacterized ciliary protein in neural development, with...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $427,625 Project Grant to the University of Wisconsin–Madison (UW-Madison) effective June 1, 2025, through May 31, 2027, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This project aims to identify cell-type-specific and developmental-stage-specific ubiquitinated proteins in UBE3A (ubiquitin protein ligase E3A) mutant mice to...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Van Andel Research Institute $123,163 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) Project Grant program, with an award date of June 1, 2025 and completion date of September 26, 2025. This research initiative focuses on identifying cortical neuronal vulnerability and resilience in Parkinson's disease through advanced molecular and genomic...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Washington University in St. Louis a Project Grant of $488,232 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective August 1, 2025, through July 31, 2030. This award funds a five-year investigator-initiated research project titled "Exploring Activity-Dependent Regulation of Intra and Intercellular Mitochondrial...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $438,625 to the University of California, San Diego under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) on August 7, 2025, for an exploratory research project extending through July 31, 2027. This project grant supports basic and translational neuroscience research aimed at characterizing a novel pro-survival mechanism in neurons exposed...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $415,717 Project Grant to the University of Wisconsin-Madison on March 10, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. This award supports a two-year research project through February 28, 2028, investigating the role of vimentin in adult mouse hippocampal neurogenesis. The research will elucidate the mechanisms by which vimentin, an intermediate filament protein, regulates neural stem cell function and behavior, including its involvement in protein trafficking, cellular protein quality control through aggresome formation, and asymmetric cell division that preserves neural stem cell rejuvenation. The funded research will generate novel scientific insights into how vimentin facilitates quiescence exit and regulates the proliferation asymmetry between daughter cells of dividing neural stem cells. These findings are intended to advance understanding of adult neurogenesis regulation and identify potential therapeutic targets for enhancing cognitive function during aging and neurodegenerative disease. The project will be conducted at the University of Wisconsin-Madison in Madison, Wisconsin.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $415.7k | 3/10/26 |