The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $211,875 Project Grant (CFDA 93.853) to New York University (NYU) School of Medicine to study the neuroanatomical abnormalities associated with repetitive head impacts in former American football players. The goal is to leverage neuroimaging data from NINDS' Diagnostics, Imaging, and Genetics Network for the Objective Study and Evaluation of CTE (DIAGNOSE CTE) research project to investigate morphological changes in the brain, including the ventricles, perivascular spaces, and gray/white matter, which may be linked to the neuropathological hallmarks of chronic traumatic encephalopathy (CTE). The research aims to identify potential biomarkers for the early detection of CTE during life, which could enable the development of appropriate treatments and interventions. The award period runs from January 1, 2025 to December 31, 2026.