This federal Project Grant award, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to further develop and optimize optogenetic spinal cord stimulation as a therapeutic strategy for promoting functional recovery in rats with severe spinal cord injuries. The $327,824 award, effective July 1, 2024 through June 30, 2029, will support research conducted...
This federal Project Grant award for $586,525.00, awarded on August 15, 2024 by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports the development of a non-invasive infrared light therapy and medical device to treat spinal cord injury. The primary research aims to attenuate the acute injury and inflammatory response in the initial 24 hours following spinal...
This $391,250 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, supports research aimed at developing effective therapeutic strategies for spinal cord injury (SCI) recovery. The key objectives are to: 1) Temporally regulate PTEN (phosphatase and tensin homolog) knockdown after SCI to promote axon regeneration while avoiding...
The University of Washington received a $541,109 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The 5-year grant, effective January 1, 2025, aims to demonstrate the feasibility of quantifying myelin loss and recovery in ischemic stroke patients using a novel magnetic resonance imaging (MRI) technique called single-point macromolecular...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will provide $506,696 to the University of Washington to conduct research on the microvascular response to traumatic spinal cord injury (SCI) in adult, middle-aged, and aged rats. The research aims to (1) monitor the spatial and temporal development of hypoperfusion in the...
This federal Cooperative Agreement award, totaling $2,354,442.00, was granted by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award aims to develop a system for closed-loop vagus nerve stimulation (VNS) therapy paired with lower limb rehabilitation to enhance recovery of gait function in individuals with chronic spinal cord injury (SCI). The...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, aims to develop innovative magnetically responsive drug delivery electrospun fibers to improve regeneration after spinal cord injury (SCI). The total funding amount is $151,559.00 over the period from August 3, 2024 to July 31, 2026. The primary recipient, Rensselaer...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to understand the molecular mechanisms regulating axon regeneration after spinal cord injury. The $1,006,322 award to the University of California, San Diego will fund experiments using a novel patch-based single-cell RNA sequencing approach to refine a regeneration...
This $238,500 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will fund research to investigate the use of epidural spinal cord stimulation (SCS) to restore bladder function in cats with chronic spinal cord injury (SCI). The key objectives are to evaluate if SCS can elicit both micturition and continence reflexes in cats with chronic...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $234,949 to Yale University to conduct research on mechanisms that support raphespinal tract plasticity and regeneration after spinal cord injury. The objectives are to use anatomy, spatial transcriptomics, and intersectional in vivo chemogenetics to define the capacity and...