The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services, awarded a $4,528,840 Project Grant to The Salk Institute For Biological Studies under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The three-year award beginning August 19, 2022 will fund research to functionally dissect cerebellar output circuits that orchestrate limb motor control. Specifically, the grantee will...
This Project Grant award of $1,208,677.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at Harvard Medical School to investigate the diverse cell types and specialized circuitry of the cerebellar cortex. The primary goal is to clarify how different subtypes of cerebellar neurons contribute to signal processing and behavior, with the aim of...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $676,388 to St. Jude Children's Research Hospital Inc. to conduct research on how polarity signals coordinate neuronal differentiation and nuclear organization. The key aims of the research are to define how the proteins SIAH2 and PARD6A regulate chromatin compaction and nuclear...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $503,439 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Colorado-Denver to conduct research on the functional roles of inhibitory cerebellar outputs. This 4-year project aims to advance the understanding of how the cerebellum, a critical region for motor control, tunes its own teaching signals and actuates motor control through...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will fund research to develop a human cerebellar organoid model of Spinocerebellar Ataxia Type 1 (SCA1). The total award is $226,139, with a project period from July 1, 2025 to June 30, 2027. The research aims to use induced pluripotent stem cell (iPSC) lines from SCA1 patients and controls...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $637,820 to the Research Institute at Nationwide Children's Hospital to conduct forward genetic analysis of cortical circuits and structure in the mammalian neocortex. The research aims to identify novel genes responsible for proper development of the cerebral cortex and basal...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will fund research to investigate the developmental transition of neural stem cell niches in the human brain. The $1,180,687 award, effective August 1, 2025 through July 31, 2033, will be provided to The Regents of the University of California, San Francisco (UCSF) to characterize the...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $1,008,977.00 to the Regents of the University of California, San Francisco to conduct research on the developmental topology of the human cerebral cortex. The key objectives are to understand human brain development and the origins of neurodevelopmental diseases by studying...
This Project Grant award of $1,062,726 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to determine the mechanisms underlying the folding of the developing cerebral cortex in human infants. The study will use longitudinal MRI data from preterm infants and fetuses to assess how patterns of cortical expansion relate to the emergence of...
This federal Project Grant award of $604,852.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to investigate the role of glial progenitor cells in the initiation and recurrence of medulloblastoma, the most common malignant childhood brain tumor. The research aims to advance the understanding of tumor heterogeneity,...