This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $233,250.00 to The Washington University to investigate the potential of hyperpolarized 13C magnetic resonance spectroscopic imaging (HP 13C MRSI) and ultra-short echo time magnetization transfer (UTE-MT) imaging to non-invasively study the role of lactate metabolism and...
This federal Project Grant award of $694,369 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program supports a multi-scale, multi-modal, longitudinal imaging study to examine the association of cognitive function with changes in brain function, anatomy, and neuronal integrity in patients with multiple sclerosis (MS). The study aims to utilize advanced MRI...
The federal Project Grant award R01NS134849, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA program 93.853, supports the development and optimization of a rapid and robust quantitative magnetic resonance imaging (MRI) technique for high-resolution volumetric brain imaging. The $621,617 award, with a project period from Sep 12, 2024 to Jun 30, 2029, aims to leverage expertise in MRI, machine learning, and pulse sequence optimization to advance MR...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $654,287 to the Icahn School of Medicine at Mount Sinai to develop a computational model of neurocognitive impairment in multiple sclerosis (MS). The goal is to provide a psychometrically valid and biologically informed update to the understanding of cognitive status in...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, provides $667,644 to the Icahn School of Medicine at Mount Sinai to conduct research on cortical demyelination and repair in early multiple sclerosis (MS). The key objectives of this 5-year project are to: 1) determine how cortical and white matter demyelination are related in...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will fund research to evaluate the therapeutic potential of hypoxia mimetics in treating inflammatory demyelinating disease, particularly multiple sclerosis (MS). The $1,949,990 award, running from August 1, 2024 to June 30, 2029, will support research to: 1) define an optimal...
This $742,352 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program is funding a collaborative research project to study the impact of childhood adversity on health outcomes for individuals with multiple sclerosis (MS), particularly among high-risk minority populations. The award supports the development of culturally-sensitive research...
This $1,550,682 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research to understand the mechanisms controlling central nervous system (CNS) myelin sheath length and their implications for neurological disorders. The primary objective is to determine how axon diameter serves as an instructive cue that triggers oligodendrocyte...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), provides $582,246 to the University of Rochester to study stem cell-based therapies for neurological and neurodegenerative disorders. The key focus is developing cutting-edge in vivo imaging and neurophysiology methods to track the structural and functional dynamics of human...
The University of Washington received a $541,109 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award will fund a 5-year clinical study to assess the feasibility of quantifying myelin loss and recovery in ischemic stroke patients using a novel magnetic resonance imaging (MRI) technique called single-point macromolecular...