The University of California, San Diego (UCSD) received a $437,250 Project Grant (R21NS135479) from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) grant program. The funding supports a 2-year research project to conduct the first pooled in vivo screening of combination gene therapies that could enhance axonal regeneration and functional recovery after spinal cord injury. The research will systematically compare the genetic knockout and overexpression of candidate genes, both individually and in combination, to identify the most effective therapeutic approaches. This novel screening method could lead to the discovery of new translational combination therapies to improve outcomes for spinal cord injury patients.
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