This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $411,941 to Drexel University to conduct research on identifying novel trunk reflex pathways and how they differ after neonatal versus adult spinal cord injury in animal models. The key objectives are to test the hypothesis that the newly discovered contralateral monosynaptic trunk reflex pathways are lost after neonatal spinal cord injury, which may help explain the better recovery of quadrupedal function observed in some animal models compared to adult injury. The 2-year project will use anatomical tracing and electrophysiological testing to examine these trunk reflex pathways and their alterations following different timing of spinal cord injury. The findings could help advance understanding of trunk motor control and recovery after spinal cord injury, potentially leading to new therapeutic approaches.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $411.9k | 7/18/23 |