Project Grant R21NS133633
Award Date 9/11/23
Completion Date 8/31/25
Dollars Obligated $430K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Atlanta, GA 30322, USA
Similar Awards
- This $443,354 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research to investigate targeting the hexosamine biosynthetic pathway as a potential treatment for pediatric brain tumors. The research aims to understand how this metabolic pathway supports the growth and apoptosis resistance of diffuse midline gliomas with the...
- This federal Project Grant award of $131,360 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is funding research at the University of New Haven to characterize the long non-coding RNA GIHCG and assess its potential as a therapeutic target for glioblastoma, the most aggressive form of brain cancer. The 4-year project aims to use CRISPR/Cas9 gene editing to...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $773,607 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Johns Hopkins University. The grant supports the development of brain-penetrant, histone evicting anthracycline drugs for the treatment of diffuse midline glioma (DMG), an aggressive and incurable form of pediatric brain cancer. The researchers are working to develop novel anthracycline...
- This federal Project Grant award of $460,940 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research conducted by the University of Texas MD Anderson Cancer Center to investigate how genetic risk factors for glioma, a type of brain cancer, impact neurodevelopmental processes and potentially promote tumor formation. The research leverages human...
- The National Institute of Child Health and Human Development (NICHD) awarded a $441,375 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Children's Hospital Medical Center in Cincinnati, Ohio. The project aims to develop "Microglia-Integrated Brain Organoids for Gaucher Disease Modeling and Therapeutic Discovery". The grant will support the creation of brain organoid models that incorporate microglia to study the mechanisms of...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $559,030 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Medical University of South Carolina. The grant supports a 5-year research project to "Uncover the Signaling Mechanisms Underlying Treatment Failure in Medulloblastoma". The objective is to investigate the signaling pathways that enable certain progenitor cell populations to...
- This federal Project Grant award of $604,852.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to investigate the role of glial progenitor cells in the initiation and recurrence of medulloblastoma, the most common malignant childhood brain tumor. The research aims to advance the understanding of tumor heterogeneity,...
- The National Institute of Neurological Disorders and Stroke (NINDS), through its Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), awarded a $420,251 Project Grant to Brigham & Women's Hospital Inc. on May 6, 2025. The grant supports the development of an encapsulated cell-based oncolytic virus therapy for the treatment of glioblastoma (GBM), the most lethal primary brain tumor. The research aims to enhance the therapeutic efficacy of engineered...
- This $245,434 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at the University of Pennsylvania to map the neural circuit connectivity of human high-grade glioma brain tumors in a mouse model. The goal is to define the whole-brain inputs onto glioblastoma cells using monosynaptic tracing techniques to understand how neuronal...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $147,486 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the Baylor College of Medicine. The grant supports research to define the role of the germline DAAM2 variant R414W in familial glioma, the most common subtype of primary brain tumor in adults. The research aims to investigate how this newly discovered DAAM2 variant contributes to glioma...