Project Grant R21NR022270
- The National Institute of Nursing Research awarded University of Massachusetts Medical School $7,345,938 on April 16, 2026, under the Nursing Research program (CFDA 93.361) to conduct a multi-state longitudinal study examining the effectiveness of school-based health centers to improve pediatric asthma care and advance health equity. The study will compare asthma outcomes and guideline-based care delivery in school-based health centers against traditional community health centers, focusing on...
- The National Heart, Lung, and Blood Institute awarded Brigham & Women's Hospital Inc. $894,314 on July 5, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop improved prediction and mechanistic understanding of chronic obstructive pulmonary disease exacerbations by integrating multi-trait genetics, proteomics, and deep learning methods. The research comprises three specific aims. In Aim 1, the recipient will develop a multi-trait polygenic risk score integrating...
- The National Institute of Nursing Research awarded the University of Pennsylvania $3,002,821 on January 30, 2026, under the Nursing Research program (CFDA 93.361) to investigate which interventions most effectively reduce hospital nurse burnout. The research will examine the relationship between organizational and individual interventions implemented nationwide to address nurse burnout and their effectiveness in reducing burnout at the hospital and individual nurse levels. The study integrates...
- The National Institute of Nursing Research, part of the Department of Health and Human Services, awarded The Johns Hopkins University $7.381 million on September 11, 2025 to conduct a randomized controlled trial of food-based interventions for obesity treatment in adults with food insecurity. The study enrolls 300 adults with obesity and food insecurity in a three-arm parallel design. Participants receive one of three interventions: behavioral weight loss (BWL) treatment alone, BWL combined with...
- The National Institute of Nursing Research awarded the University of Pennsylvania $406,250 on August 21, 2026, under the Nursing Research program (CFDA 93.361) to evaluate the impact of the nurse work environment on outcomes for hospitalized older adults living with Alzheimer's disease and related dementias. The recipient will conduct a mixed-methods sequential explanatory study examining modifiable organizational features central to care quality, including nurse autonomy and authority to...
- The National Institute of Allergy and Infectious Diseases awarded Brigham & Women's Hospital Inc. $724,190 on July 10, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant funds research into maternal-neonatal transmission of protective resolution mechanisms for lung inflammation. The investigator-initiated project examines how maternal milk confers immunity to allergic diseases and respiratory infections in infants through specialized pro-resolving...
- The National Institutes of Health National Heart Lung and Blood Institute awarded New York University $201,728 on March 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct research examining mechanisms contributing to functional recovery across the care cascade for respiratory failure. The research addresses how patient-level social determinants recorded at hospital admission, unit-level care processes during hospitalization, and community-level environmental...
- The Department of Health and Human Services National Institutes of Health National Institute of Nursing Research awarded $6,554,392 to The Johns Hopkins University on July 1, 2026, under the Nursing Research program (CFDA 93.361) to conduct an intersectional mixed methods study examining how structural gendered racism-related policies impact depression and anxiety among US- and foreign-born Black, Latina, and White women. The research uses novel theoretical frameworks including...
- The National Institute of Nursing Research awarded The Trustees of The University of Pennsylvania $4,241,658 on January 29, 2026, under the Nursing Research program (CFDA 93.361) to evaluate multi-level interventions addressing nurse burnout across hospital settings. The study employs a repeated cross-sectional design spanning 20 years of data collection from approximately 535 hospitals in California, Florida, New Jersey, and Pennsylvania. Data collection timepoints occur at 2006, 2016, 2024,...
- The National Heart, Lung, and Blood Institute awarded Brigham & Women's Hospital Inc. $372,635 under NIH Project Grant R21HL188684 on August 15, 2026, to develop a network proximity-based drug repurposing pipeline for chronic obstructive pulmonary disease. The award funds two integrated aims. In Aim 1, the recipient will build an updated COPD disease module by integrating genome-wide association studies and multi-omics data into the human protein interactome, using a proximity-based...
The National Institute of Nursing Research awarded Brigham & Women's Hospital Inc. $492,250 on July 22, 2026, under the Nursing Research program (CFDA 93.361) to investigate ultra-processed foods as a modifiable risk factor for respiratory exacerbations. The research combines artificial intelligence methodologies to quantify food processing with deep clinical and molecular phenotypes from the COPDGene longitudinal cohort study. The work addresses how variability in food processing across ultra-processed food (UPF) subgroups affects pulmonary outcomes, examining whether chronic systemic inflammation mediates the relationship between UPF consumption and respiratory exacerbation frequency and severity. Specific aims include quantifying the association of AI-scored UPF consumption with respiratory exacerbations and lung function decline, identifying inflammatory markers that may explain UPF impacts on the lungs, and characterizing how UPF subgroups differentially associate with pulmonary outcomes. Performance occurs in Boston, Massachusetts, with a period of performance from July 22, 2026, through July 31, 2028. This is a Project Grant, the standard research mechanism under the Nursing Research program supporting investigator-initiated science from eligible institutions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $492.3k | 7/23/26 |