Project Grant R21MH140677
- The National Institute of Mental Health awarded The General Hospital Corporation, doing business as Massachusetts General Hospital, $855,983 on March 13, 2026, under the Mental Health Research Grants program (CFDA 93.242) to evaluate the impact of an electronic partner notification (EPN) platform for sexually transmitted infections in Suffolk County, Massachusetts—an Ending the HIV Epidemic priority area. The award funds research examining how Massachusetts Department of Public Health's...
- The National Institute of Mental Health awarded The General Hospital Corporation (Massachusetts General Hospital) $790,560 under the Mental Health Research Grants program (CFDA 93.242) on April 1, 2026. The award funds development of advanced artificial intelligence models to predict differential antidepressant treatment responses by integrating electronic health records and genomic data. Aim 1 involves building a large language model-based, human-in-the-loop active learning framework to...
- The National Institute of Mental Health awarded The General Hospital Corporation (Massachusetts General Hospital) $824,404 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop machine learning models that integrate clinician-conducted suicide risk assessments with electronic health record data to improve prediction of suicidal behavior and guide precision interventions in outpatient behavioral health settings. The research leverages routine clinical...
- The National Institute of Allergy and Infectious Diseases awarded The General Hospital Corporation (doing business as Massachusetts General Hospital) $830,944 on July 17, 2026, for research on novel methods to inform HIV/TB clinical trial development under the Allergy and Infectious Diseases Research program (CFDA 93.855). The funded research advances value-of-information (VOI) analytic methods within microsimulation models of HIV and TB to address clinical trial design priorities. The project...
- The National Institute of Allergy and Infectious Diseases awarded The General Hospital Corporation (doing business as Massachusetts General Hospital) $824,998 on September 3, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate natural killer cell targeting of HIV-1 reservoir cells. The award funds research into the immune mechanisms that recognize and eliminate HIV-1 reservoir cells—a small subset of CD4 T cells harboring integrated HIV-1 DNA that...
- The National Institute of Mental Health awarded The General Hospital Corporation (doing business as Massachusetts General Hospital) $839,023 on April 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop and validate computer vision techniques for suicide risk detection in emergency department settings. The award funds development of automated analysis of standardized skin images to identify and assess the severity of self-injury marks as predictors of prospective...
- The National Institute of Child Health and Human Development awarded The General Hospital Corporation (Massachusetts General Hospital) $1,503,452 under the Child Health and Human Development Extramural Research program (CFDA 93.865) on February 9, 2026. The research project, titled "Mechanistic Intersection Between Placental Vascular and Newborn Neuronal Development," investigates adverse neurodevelopmental outcomes in HIV-exposed but uninfected children born to pregnant people with...
- The National Institute of Mental Health awarded Massachusetts General Hospital $453,750 under the Mental Health Research Grants program (CFDA 93.242) on September 1, 2026, to develop a closed-loop system for assessing target network engagement using concurrent transcranial magnetic stimulation and functional MRI. The recipient is developing a flexible radiofrequency coil array (the RF Cap) that enables functional MRI acquisition simultaneously with transcranial magnetic stimulation in a...
- The National Institute on Drug Abuse awarded The General Hospital Corporation (Massachusetts General Hospital) $740,451 under the Drug Use and Addiction Research Programs (CFDA 93.279) on May 1, 2026, to evaluate community health worker support for improving tobacco use disorder outcomes in Medicaid beneficiaries with serious mental illness. The research will enroll 937 adults with serious mental illness and tobacco use disorder who receive behavioral healthcare through Medicaid accountable care...
- The National Institute of Allergy and Infectious Diseases, part of the Department of Health and Human Services National Institutes of Health, awarded $1,032,783 to Massachusetts General Hospital on August 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support research on broadly neutralizing antibodies against HIV. The research, led by Dr. Alejandro Balazs at the Ragon Institute of MGH, MIT & Harvard, focuses on engineering the immune system through gene...
The National Institute of Mental Health awarded The General Hospital Corporation (doing business as Massachusetts General Hospital) $453,750 on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop and test an optimized case management intervention for people living with HIV who face barriers to adherence to care. The project, titled the OPTI-HEAT Study, will develop a multi-level case management implementation toolkit designed to improve viral suppression and retention in care for people living with HIV experiencing mental health comorbidities, substance use, homelessness or unstable housing, and language or cultural barriers. The toolkit will include components for both patients and care team members, developed in conjunction with community partners. The research team will conduct a mixed-methods study to assess determinants of viral suppression, analyze historical data from Massachusetts General Hospital's HIV Enhanced Access to Treatment (HEAT) Program, and conduct semi-structured qualitative interviews. The multidisciplinary investigator team includes expertise in clinical epidemiology, HIV program leadership, qualitative research, and implementation science. Performance occurs in Boston, Massachusetts, with a period of performance from August 1, 2026, through July 31, 2028. This is a Project Grant, classified as an exploratory and developmental research award, supporting up to three years of investigator-initiated work addressing implementation science innovations to reach people living with HIV who are hardest to engage in care.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $453.8k | 7/29/26 |