Project Grant R21MH138855
- This Project Grant award, valued at $183,118, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH). The funded project, titled "Integrating Genomics and EHR to Accelerate Precision Psychiatry," aims to address key limitations in translating genomic findings to clinical practice in psychiatric disorders. The project will...
- The National Institute of Mental Health (NIMH) awarded a $1,244,076 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Spatial Genomics, Inc. located in Pasadena, California. The purpose of this 2-year award, with a period of performance from June 1, 2025 to May 31, 2027, is to develop next-generation reagents and assays to scale up the multiplexity of the company's Gene Positioning System (GenEPS) platform. This spatial genomics technology, based on sequential...
- This $129,290 Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research at Massachusetts General Hospital (MGH) to analyze phenotypic, genetic, and neurobiological data from over 43,000 participants with autism spectrum disorder (ASD) and schizophrenia (SCZ). The goal is to better understand how genetic variation associated with intellectual disability, ASD, and SCZ maps onto developmental...
- This federal Project Grant award for $412,500.00, provided by the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 - Biomedical Research and Research Training program, supports a research program to improve the interpretation of rare genetic variants. The awardee, The General Hospital Corporation doing business as Massachusetts General Hospital (MGH), will use state-of-the-art computational methods to enhance existing annotation tools for predicting the impact of...
- The National Institute of Mental Health (NIMH) awarded a $314,113 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Physical Sciences Inc. (PSI) of Andover, MA. The grant will fund the development and demonstration of a high-speed, multicolor confocal fluorescence imager to simultaneously capture multi-wavelength signals and display them as separated or merged multicolor images and 3-D stacks. This technology innovation will enable mapping of complex neuronal network...
- The National Institute of Mental Health (NIMH) awarded a $854,029 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), for the project "Multimodality Adaptive Intervention for Post-Inpatient Hospitalization Suicide Risk Reduction." The award, effective September 1, 2025 and running through August 31, 2030, will fund the development and evaluation of a multimodal...
- This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $714,615 to New York University School of Medicine to conduct research on dissecting the role of non-coding repeats in the genetics of psychiatric disorders like schizophrenia and bipolar disorder. The key objectives are to: Fine map regulatory features of a repeat expansion within the CACNA1C gene, which has been strongly associated with...
- This federal Project Grant award of $702,928 was provided by the National Institute of Mental Health (NIMH), which administers the Mental Health Research Grants program (CFDA 93.242), to The Trustees of the University of Pennsylvania, doing business as the Clinical Practices of the University of Pennsylvania. The grant supports research to enhance the integration of multi-organ imaging data of the brain and body, psychiatric genetic studies, and functional genomic data resources to uncover...
- The U.S. National Institute of Mental Health (NIMH) awarded a $271,688 project grant under the Mental Health Research Grants program (CFDA 93.242) to Virginia Commonwealth University (VCU). The grant supports research to better understand normal and disease processes in the brain using extracellular vesicles (EVs) isolated from peripheral blood samples. The key objectives are to catalog the RNA cargo of brain-derived EVs and derive novel biomarkers for schizophrenia. This research aims to...
- The National Institute of Mental Health (NIMH) awarded a $156,656 Project Grant under the Mental Health Research Grants (CFDA 93.242) program to The General Hospital Corporation (doing business as Massachusetts General Hospital) to advance functional MRI (fMRI) techniques for mapping brain activity across cerebral cortical layers. The project aims to validate and benchmark a "linescan fMRI" method that can achieve higher spatial resolution than conventional laminar fMRI, enabling...
The National Institute of Mental Health (NIMH) awarded a $206,250 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), for the project "A COPY NUMBER VARIANT DISCOVERY PIPELINE FOR INTEGRATED GENOME-EXOME SEQUENCING". The award period runs from Sep 1, 2025 to Aug 31, 2027. The project aims to develop a pipeline to detect copy number variants (CNVs) across the genome and exome at high resolution, in order to systematically assess the impact of CNVs on neuropsychiatric disorders, especially across diverse global populations. The grant leverages advanced sequencing techniques, including blended genome-exome (BGE) sequencing, to enable comprehensive CNV discovery and analysis.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $206.3k | 8/25/25 |