This Project Grant award from the National Institute of Mental Health (CFDA 93.242 - Mental Health Research Grants) provides $196,460.00 to Emory University to support research aimed at elucidating the neural substrates underlying novelty-related social investigation behaviors in mice. The project leverages sophisticated in vivo recording techniques, projection-specific optogenetic stimulation, and computational approaches to determine how social recognition information encoded in the ventral...
This $135,989 Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants (CFDA 93.242) program, aims to comprehensively map the influence of gonadal hormones on network-level coding of proactive social behavior and related social variables (context, partner) in mice. The research conducted at Princeton University will develop new computational analysis methods for social behavior and new optical tools for recording neural activity across...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will support research to investigate the role of sexually dimorphic arginine vasopressin (AVP) circuits in the control of social interest. The $727,479 award to the Georgia State University Research Foundation Inc. will fund a 5-year study examining how AVP cell activity in the bed nucleus of the stria terminalis (BNST) interacts with the lateral septum...
This $185,625 Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), supports research on the neural mechanisms underlying socially transmitted aggression in mice. The primary objectives are to: 1) investigate the function of medial amygdala (MeApv) neurons in socially transmitted aggression using chemogenetics, and 2) examine the role of synaptic plasticity at MeApv-VMHvl synapses in modulating socially transmitted...
The federal Project Grant award R01MH136228, with a total funding amount of $829,966.00, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The overall objective of this research project is to investigate the neural basis of social information processing, with a focus on understanding how the brain encodes and integrates social characteristics such as familiarity and hierarchy. The project will leverage innovative...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under CFDA Program 93.242 - Mental Health Research Grants supports research to investigate the circuit-specific androgen receptor regulation of hippocampal neuronal excitability. The $178,087 award to Michigan State University (MSU) aims to determine the signaling mechanisms by which androgen receptors reduce ventral hippocampal-nucleus accumbens circuit excitability in both male and female mice. The project...
This Project Grant award from the National Institute of Mental Health (NIMH), under CFDA Program 93.242 Mental Health Research Grants, provides $417,200.00 in funding to Emory University to characterize and manipulate large-scale neural activity patterns in the brain. The key objectives are to: 1) Use simultaneous wide-field optical imaging and functional MRI to determine if patterns of quasi-periodic brain activity observed in fMRI reflect underlying neural dynamics, and 2) Assess whether...
This $1,122,846 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research to investigate the role of hippocampal HCN channels in mediating sex-dependent behavioral responses to social defeat stress. The research team at Augusta University Research Institute, Inc. (dba Georgia Health Sciences) will use male and female mouse models of social avoidance to test the hypothesis that changes in neuronal...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), provides $301,524 to support research aimed at decoding the specificity of social drives. The primary objectives are to determine if and how the ventrolateral area (VMHVL) of the brain encodes distinct social motivational states, using advanced in vivo...
This $127,305 Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), supports research to investigate the role of frontal parvalbumin interneuron maturation in the development of attentional abilities from adolescence to adulthood. The research aims to characterize how the maturation of these specific neurons in the anterior cingulate cortex of the frontal lobe is associated with the synchronization of neural...