Project Grant R21HL181072
- The Research Foundation For The State University Of New York, doing business as Stony Brook University, received a $337,284 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) to develop a single-cell spatial multiplex in situ tagging (MIST) technology and apply it to kidney biopsy samples for functional proteome studies. This novel technology will enable the measurement of hundreds of functional proteins, including biomarkers, signaling...
- This $734,722 Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports a randomized controlled clinical trial to assess the impact of disclosing systolic blood pressure polygenic risk scores on blood pressure control, healthy lifestyle adherence, and cardiometabolic health among 300 hypertensive adults aged 18-55 in the United States. The study aims to evaluate whether providing individuals with information about their...
- This $165,364 federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to integrate novel contextual and genomic blood pressure measures to enhance cardiovascular disease prediction and management in young adults aged 18-39 years. The key products and services to be delivered under this 2-year award include: Identifying novel ambulatory blood pressure patterns that capture dynamic responses to everyday factors and...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $190,491 to Beth Israel Deaconess Medical Center, Inc. to conduct research on plasma protein markers of the blood pressure response during exercise and their relation to incident hypertension and cardiovascular disease. The project aims to identify circulating proteins associated with exercise blood pressure that could serve as predictive markers for future...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to study the effects of structural racism on disparities in environmental exposures and cardiovascular disease (CVD) outcomes. The $123,368 award to The Research Foundation For The State University Of New York (UEI LVVEB3CF8MB8), effective September 16, 2025 through August 31, 2030, will leverage New York's all-payer hospital database and integrate it with primary data...
- The National Heart, Lung, and Blood Institute (NHLBI), which is part of the National Institutes of Health (NIH), awarded a $688,525 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the University of California, San Diego (UCSD). The grant, titled "Blood Pressure Control Advancing Refugee Health Equity (BPCARE): An RCT of Adherence", aims to develop and test a behavioral intervention to improve antihypertensive medication adherence and blood pressure...
- The University of Florida received a $1,410,766 Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to conduct a mixed methods comparative effectiveness analysis on the implementation of new blood pressure (BP) control technologies and strategies during the COVID-19 pandemic. The study aims to leverage the PCORnet Blood Pressure Control Laboratory to examine the extent and variability of BP control implementation across healthcare...
- This $285,195 project grant was awarded on August 20, 2025 by the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to Brigham & Women's Hospital Inc. to support research on improving hypertension management through patient self-titration of antihypertensive medications. The project aims to adapt this intervention to the U.S. primary care context by assessing patient preferences, provider perspectives, and integration with electronic health records and...
- This federal Project Grant award of $649,678, provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), supports the development of a high-speed, wearable speckle contrast optical spectroscopy (SCOS) system for cuffless blood pressure monitoring. The project aims to convert the existing benchtop SCOS technology into a wearable device capable of multi-hour ambulatory monitoring, and to test the technique in a wider range of subjects,...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $1,084,359 to Nusirt Sciences, Inc. to conduct clinical validation of the fixed combination drug product NS-0200 for the treatment of hypertension. The award will support research activities from September 15, 2025 through June 30, 2027 to evaluate the efficacy and safety of this novel hypertension treatment. Hypertension is a major global health issue, affecting...
The Research Foundation for the State University of New York (RFSUNY), doing business as Stony Brook University, received a $237,750 Project Grant from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to investigate the association between blood biomarkers and adverse cardiovascular and kidney outcomes in individuals with hypertension. The 3-year project aims to obtain and analyze blood specimen data from the SPRINT and ACCORD clinical trials to identify circulating protein biomarkers associated with decline in kidney function and adverse cardiovascular events. The research seeks to enhance understanding of which hypertension patients are at higher risk for these outcomes and how intensive blood pressure lowering may mitigate the effects of the identified biomarkers. This work is intended to inform guidelines for blood pressure management in hypertension patients with and without diabetes or chronic kidney disease.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $237.8k | 8/26/25 |