This $225,600 Project Grant was awarded on September 1, 2024 by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The purpose is to engineer a lab-on-a-particle platform to measure platelet function, which has the potential to improve the diagnosis and treatment of bleeding disorders. Specifically, the University of Colorado-Denver, a major public research university, will synthesize peptide-functionalized hydrogel microparticles to measure platelet adhesion, activation, aggregation, and contraction in a high-throughput format. This innovative platform aims to increase the reliability and reproducibility of platelet function testing compared to conventional methods. The project will be conducted over a 22-month period through May 31, 2026.
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