Project Grant R21HD113774
Award Date
9/1/24
Completion Date
8/31/26
Dollars Obligated
$430K
Federal Agency
National Institute of Child Health and Human Development
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Massachusetts, USA
Similar Awards
The National Institute of Child Health and Human Development (NICHD) awarded a $760,617 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Children's Hospital Corporation, doing business as Boston Children's Hospital. The grant funding will support a 5-year research project titled "Understanding the Mechanism of Pre- to Naive- to Formative-Pluripotency Transitions". The research aims to identify key transcription factors and...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under CFDA program 93.865 Child Health and Human Development Extramural Research, supports a mixed-methods longitudinal study titled "Prenatal Exposure to Maternal Incarceration and Infant and Toddler Health and Development". The $158,216 award will fund research to analyze data from the "Birth Beyond Bars" study, examining the impact of prenatal exposure...
This $178,000 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to develop an early life phenotyping framework for very preterm infants. The research aims to create 'perinatal phenotypes' by integrating variables such as reason for preterm birth, intrapartum care, and neonatal presentation, and then determine how these phenotypes contribute to...
This $148,568 federal Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training Program will support research to elucidate the role of chromatin structures in genomic imprinting. The project, led by Harvard University, aims to investigate the regulatory mechanisms and functional implications of allele-specific chromatin structures in the regulation of the MEST-COPG2 imprinted domain, which is associated with...
This federal Project Grant award, provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under CFDA Program 93.865 (Child Health and Human Development Extramural Research), supports research to evaluate the mechanisms of cell-free fetal DNA signaling in the promotion of labor. The $139,446 award, with a performance period from August 2024 to January 2025, will enable the grantee, Mayo Clinic, to pursue two key research objectives: 1) Evaluating...
This federal Project Grant award of $2,442,535 was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The goal of this 5-year project is to provide critically-needed evidence on how to implement newborn genomic sequencing, manage findings, and reanalyze data to ensure it provides lifelong benefits to individuals and advances public health. The key...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $202,864 to the University of Wisconsin - Madison to investigate the role of histone demethylases KDM3A and KDM3B in primordial germ cell (PGC) development. The research aims to elucidate how the removal of repressive epigenetic modifications, such as H3K9me2, impacts PGC specification and...
The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
This Project Grant award of $1,410,779, provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 "Child Health and Human Development Extramural Research", supports the development of epigenomic liquid biopsy methods for early detection and prediction of clinical trajectories related to preterm birth (PTB). The awardee, Magee-Womens Research Institute and Foundation, is collaborating with the University of Pittsburgh to...
This federal Project Grant award for $378,123 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to identify and test mechanisms that establish transcriptional regulatory potency in early embryos. The primary activities include using genomic methods like PRO-seq, DREG, and OMNI-ATAC to characterize transcriptionally active regulatory elements, DNA accessibility, and...