Project Grant R21GM159205
- This federal Project Grant award of $349,566 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of a Spotting-Free Nano-Oscillator Array (SFNOA) technology for high-throughput, label-free quantification of ligand binding kinetics to transmembrane proteins in their native states. The key products and services delivered through this award include: Integration of innovative technologies...
- This $445,000 Project Grant award, funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports a research project focused on leveraging long-read transcriptomics to elucidate transcriptome complexity and advance genomic medicine. The central objective is to harness the power of long-read RNA sequencing to provide unprecedented insights into alternative splicing and its impact on gene products, which is...
- This federal Project Grant award for $390,000.00 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports the development of new tools for high-throughput characterization of extracellular RNA, DNA, and vesicles in bodily fluids. The primary objectives are to: 1) develop methods to reliably control for technical variability, RNA degradation, and complexity in cell-free RNA (cfRNA) analysis, including...
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $306,700 Project Grant to Rybodyn, Inc. for the development of a novel spatial biology platform for cost-effective and scalable protein profiling. The goal of this 12-month project is to create a non-destructive, image-free spatial biology platform that can achieve sub-cellular resolution of protein presence and abundance using proprietary barcoded tags...
- This federal Project Grant award of $459,250.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to develop a systematic approach for detecting regulatory RNAs and their functional motifs based on RNA-protein interactions. The key research objectives include: Investigating whether RNA regulates the genomic occupancies of chromatin-associated proteins (CAPs). Employing an...
- The National Institute of General Medical Sciences (NIGMS) has awarded a $389,653 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The Research Foundation for the State University of New York (RF-SUNY), doing business as Rf-SUNY At The University At Albany. This 5-year project, starting on January 1, 2025, aims to develop a transdisciplinary research program centered around AI-supported biosensing and precision therapeutics using DNA nanotechnology and...
- This federal Project Grant award, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports advanced quantitative analyses of long-read RNA sequencing data at both the bulk and single-cell levels. The $424,264 award, effective June 1, 2025 through May 31, 2030, will enable the University of Michigan to build upon their expertise in long-read sequencing bioinformatics and deliver new insights into...
- This federal Project Grant award of $427,625 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop capillaric microfluidics for integrated sample preparation in miniaturized mass spectrometry (mini-MS) systems. The research will focus on creating portable, self-powered, and self-regulated sample preparation capabilities to improve the versatility and applicability of mini-MS instruments for...
- The federal Project Grant award of $350,000 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) is supporting the development and demonstration of a novel enzyme-based, single-molecule protein sequencing system by Electronic Biosciences, Inc. This innovative platform leverages enzyme-driven processing and sequencing of individual proteins and peptides, combined with advanced bioinformatics, to achieve high...
- This $1,737,000 Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports the development of innovative single-cell genomics technologies for joint analysis of regulatory dynamics and transcriptional states. Key objectives include: Developing multiomics tools to measure rates of epigenomic changes (DNA methylation, demethylation, oxidative damage, DNA repair) and relate these to...
This federal Project Grant award of $436,001 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to create a novel spatial transcriptomics platform that increases accessibility and efficiency. The key products and services to be delivered include: Developing a spatial transcriptomics platform using a simple filter array format that increases sequencing depth per spatial barcode, enabling more data per capture bead compared to existing technologies. This addresses limitations of current spatial transcriptomics methods that either require specialized equipment/skills or provide limited sequencing data per spatial location. Encoding the spatial barcode pattern directly into the sequencing data, simplifying the spatial decoding process and further increasing accessibility of the technology for the wider biomedical community. The award period runs from August 1, 2025 to July 31, 2027, and the project is being led by the Research Foundation for the State University of New York (RFSUNY), doing business as Stony Brook University, a prominent non-profit research institution with extensive experience in securing federal grants and contracts across diverse scientific domains.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $436.0k | 8/1/25 |