Project Grant R21EY035976

Award Date 6/1/24
Completion Date 5/31/26
Dollars Obligated $208K
Funding Federal Agency
Office of the Director
Awarding Federal Agency
National Eye Institute
Federal Grant Program
93.310
Assistance Type
Project Grant
Place of Performance
Farmington, CT 06032, USA

The University of Connecticut Health Center (UCHC) was awarded a $208,073 federal Project Grant from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) to conduct research on "Targeting Corneal Schwann Cells to Counteract Against Toxin Injury". The grant, which runs from June 1, 2024 to May 31, 2026, aims to identify novel druggable targets in corneal Schwann cells to promote axonal regeneration and restore corneal sensation following exposure to chemical warfare agents like sulfur mustard. This innovative research seeks to develop an effective therapeutic countermeasure against these devastating ocular injuries by exploiting the regenerative potential of corneal Schwann cells. The project will evaluate FDA-approved drugs for their ability to support rapid and widespread axonal regeneration during both acute and chronic stages of injury in animal models.

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