Project Grant R21ES037893
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $414,368 to the University of California, Davis under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 23, 2025, with a completion date of June 30, 2027. This award funds research investigating the molecular mechanisms underlying persistent effects of early life exposure to aeroallergens and air pollution on lung function and remodeling. Using...
- Federal Project Grant Award Summary The University of California, Davis received a $749,640 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded April 1, 2026, with completion targeted for March 31, 2031. This award funds mechanistic research investigating the interplay between TET1-mediated epigenomic mechanisms and N6-methyladenosine (m6A) RNA modification in pulmonary inflammation induced by...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the La Jolla Institute for Immunology a Project Grant of $764,868 (awarded April 1, 2026; completion date March 31, 2031) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate house dust mite (HDM) allergen-specific T cell subsets in allergic disease and asthma. The research addresses a significant public health problem affecting approximately one-third of the...
- Federal Project Grant Award Summary George Washington University received a $444,920 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 1, 2025, through August 31, 2030. This award funds investigator-initiated biomedical research designed to elucidate the role of endogenous retroviruses (ERVs) in the development of type 2-dominated allergic inflammation in the lungs,...
- Federal Grant Award Summary The National Institutes of Health (NIH) Office of the Director awarded the University of Colorado-Denver a Project Grant of $1,395,741 under the Trans-NIH Research Support program (CFDA 93.310) for the period September 1, 2025 through August 31, 2028. The award supports research investigating mast cell activation as a common mechanism underlying pulmonary toxicity from chemical threat agents of concern to the Department of Homeland Security. The research will...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded a $765,348 Project Grant to the University of California, Davis on April 14, 2026, for research investigating pollutant-adsorbed nanoplastics (PANs) and their health impacts through inhalation exposure. Under the Environmental Health program (CFDA 93.113), the research will develop and optimize label-free detection methodologies using advanced imaging techniques, including enhanced dark...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded $249,000 to the University of Colorado-Denver under the Environmental Health program (CFDA 93.113) on July 14, 2025, for a project titled "Learning and Living with Wildfire Smoke: Creating Clean Air Environments in Schools Through Youth Participatory Action Research." This K99 mentored career development award supports Dr. D'Evelyn's training and research in environmental...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Rochester a $716,066 Project Grant on September 19, 2025, under the Environmental Health program (CFDA 93.113) to investigate the mechanisms of environmentally-induced bronchiolitis obliterans (BO). This devastating lung disease of the small airways is increasingly associated with occupational inhalation exposures to reactive diketone chemicals, particularly...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $1,006,211 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded February 17, 2026, with completion targeted for January 31, 2034. The grant supports research to elucidate how environmental chemical exposures affect mitochondrial function and interact with genetic mitochondrial disease conditions. The...
- Federal Project Grant Summary The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a collaborative research project grant of $279,959 to The Washington University (awarded May 1, 2025; completion April 30, 2028) under the Engineering program (CFDA 47.041). The research will investigate the combined chemical and biological determinants of indoor air quality by examining how building material surface composition and indoor air...
The National Institute of Environmental Health Sciences (NIEHS) awarded Washington University in St. Louis a $427,625 Project Grant effective June 1, 2026, through May 30, 2028, under the Environmental Health program (CFDA 93.113). This award funds research investigating how chemical transformations of house dust mites (HDM) and their allergens occur when exposed to indoor air pollutants such as ozone and diesel fuel chemicals. The research will employ two primary approaches: (1) utilizing chromatography-mass spectrometry to assess chemical transformations of Der P 1 (the major HDM allergen), HDM proteins, and genuine house dust, and (2) conducting acellular assays to measure associated changes in oxidative potential. The project responds to the critical public health concern that indoor air pollutant exposure contributes to significant disease burden in the United States, accounting for 400–1,100 disability-adjusted life-years per 100,000 people. The research will employ a mouse model of allergic airway inflammation to determine whether chemically altered HDM exacerbates allergic inflammatory responses through increased oxidative potential and cytokine production. The deliverables include comprehensive chemical analysis data, oxidative potential measurements, and mechanistic insights into how environmental pollutant exposure enhances HDM allergenicity, directly supporting NIEHS's mission to translate environmental health knowledge into strategies reducing disease burden and promoting population health outcomes.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $427.6k | 6/3/26 |