Project Grant R21ES037200

Award Date 1/15/25
Completion Date 1/14/27
Dollars Obligated $405K
Federal Grant Program
93.113
Assistance Type
Project Grant
Place of Performance
Pennsylvania, USA
Similar Awards
This federal Project Grant award of $428,387, provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, supports research to investigate the toxicological consequences of environmentally relevant nanoplastics. The grantee, Purdue University, has developed a novel procedure to reproducibly generate micro- and nanoplastics from common plastic waste materials, allowing for the study of fundamental mechanisms of nanoplastic...
This federal Project Grant award, provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, supports research to define the neurotoxic and neurodevelopmental health risks of per- and polyfluoroalkyl substances (PFAS). The $546,350 award, effective January 13, 2025 through October 31, 2029, aims to characterize the mechanisms by which PFAS affect brain development and function. Key objectives include defining PFAS uptake...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, is supporting research to assess the effects of microplastics and nanoplastics on intestinal health using 3D human and mouse intestinal models. The $389,229 award to Trustees of Tufts College, a private research university in Massachusetts, aims to provide a comprehensive understanding of the potential health consequences of exposure...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $704,695 to The Roskamp Institute, Inc. to investigate the neurological effects of aerosolized red tide neurotoxins. The primary goals are to determine the dose-response relationship between aerosolized exposure to the neurotoxin brevetoxin and the development of neurological symptoms, as well as whether individuals with preexisting...
The National Institute of Environmental Health Sciences (NIEHS) awarded a $390,724 Project Grant (CFDA 93.113 - Environmental Health) to the University of New Mexico (UNM) to develop a high-throughput separations platform called "Standing Wave Acoustics for Nanoplastics Separations (SWANS)". This platform will use bulk mode acoustic standing waves to rapidly enrich and isolate plastic nanoparticles from diverse samples such as bottled water, environmental water, and animal tissue....
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $429,504 to New York University (NYU) School of Medicine to characterize human exposure to microplastics during pregnancy. The overarching aim is to leverage existing infrastructure from the NYU Children's Environmental Health Study (NYU CHES) to measure and characterize microplastics in placental tissue collected from the general...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, provides $306,872 to Bioprinting Laboratories Inc. to establish a platform for high-throughput developmental neurotoxicity (DNT) testing using engineered brain organoids. The key products and services to be delivered include: Developing genetically engineered, induced pluripotent stem cells with a promoter-reporter assay system to...
The National Institute of Environmental Health Sciences (NIEHS) awarded a $200,230 Project Grant under the Environmental Health (CFDA 93.113) program to the University of South Carolina. The grant funds research to characterize the atmospheric transformation of harmful cyanobacterial algae (HABs) and investigate the mechanisms of pulmonary toxicity from inhaled HAB aerosols. The project will utilize an environmental chamber to produce and analyze transformed HAB aerosols, which will then be...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, provides $356,178.00 to Swarthmore College to conduct research on the behavioral effects of ToxCast Phase I chemicals on planarians, with the goal of determining their potential context of use. The research aims to investigate how various environmental exposures, such as chemicals and toxins, can impact biological systems and public...
The National Institute on Aging (NIA) awarded a $3,925,264 Cooperative Agreement under its Aging Research Federal Grant Program (CFDA 93.866) to the University of New Mexico's Health Sciences Center. The project, titled "PRE3BAD: Preclinical Research on Emerging Environmental Exposures, Brain Aging, and Dementia", will assess the neuropathological impacts of emerging environmental contaminants like wildfire smoke, microplastics, and heavy metals across different exposure timeframes...

This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $404,989 to The Pennsylvania State University to investigate the mechanisms by which nanoplastic particles may be transported into the brain via the olfactory system. The research aims to understand how nanoplastics, which are ubiquitous in the environment, can potentially enter the brain and impact neurological health. The key activities include in vivo studies on nanoplastic uptake and transport in the mouse olfactory system, as well as in vitro experiments to examine the interactions between nanoplastics and kinesin motor proteins responsible for axonal transport. This 2-year project, starting on January 15, 2025, seeks to provide a comprehensive understanding of nanoplastic exposure and its link to neurological disease.

Generated 8/5/25, 4:13 AM