Project Grant R21ES036946
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), will support research at Brown University to investigate the impact of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) on adult cardiometabolic disease. The $656,250 award, with a performance period from August 6, 2025 to May 31, 2029, will enable researchers to conduct an unprecedented assessment of 44 individual PFAS,...
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), provides $546,350 to fund a study to "Define the Neurotoxic and Neurodevelopmental Health Risks of Per- and Polyfluoroalkyl Substances (PFAS)". The key objectives of this 4.5-year research project are to: 1) Characterize the mechanisms by which PFAS facilitate neuronal uptake and accumulation; 2) Elucidate the...
- This federal Project Grant award, in the amount of $385,219, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health grant program (CFDA 93.113). The award supports research at the University of Rhode Island to investigate the role of albumin and other serum factors in the accumulation and toxicity of per- and polyfluoroalkyl substances (PFAS). The research aims to determine whether albumin is a key factor for PFAS distribution and...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, provides $695,853 to the Arkansas Children's Research Institute (ACRI) from December 1, 2024 to November 30, 2029. The project will investigate the impact of prenatal and postnatal exposure to per- and polyfluoroalkyl substances (PFAS) on children's development, examining the role of placental function and the potential protective...
- This Project Grant award, valued at $3,121,590.00 and funded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113), supports research conducted by Duke University to investigate the impacts of per- and polyfluoroalkyl substances (PFAS) exposure on placental function and fetal development. The key objectives of the research are to: 1) examine mitochondrial perturbations associated with PFBS (an emerging PFAS compound)...
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $121,057 to Trustees of Boston University (doing business as Boston University Medical Campus) to conduct a prospective study investigating associations between per- and polyfluoroalkyl substance (PFAS) mixtures and pregnancy outcomes among Black women. The research aims to: 1) evaluate the association of a PFAS mixture with adverse...
- This $416,750 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), will fund research at East Tennessee State University (ETSU) to investigate the effects of per- and polyfluoroalkyl substances (PFAS) on renal hemodynamics and kidney disease. The overarching goal is to determine if PFAS cause renal vasoconstriction, hypertension, and acute kidney injury, which can lead to chronic kidney...
- The University of Massachusetts Lowell received a $157,437 Project Grant from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), to study the urinary, biliary, and fecal excretion of per- and polyfluoroalkyl substances (PFAS) and the impact of dietary fiber. The project aims to investigate the extent of enterohepatic recirculation of PFAS, which contributes to their long half-lives and increased risk of adverse...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a $143,331 Project Grant to Wayne State University to investigate the molecular impacts of per- and polyfluoroalkyl substances (PFAS) exposure on male reproductive health. The research aims to use single-cell RNA sequencing and analysis of epididymal extracellular vesicles to decipher how PFAS exposure affects spermatogenesis, sperm epigenetics, and overall...
- This $313,372 federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) supports the development of an environmental sensor for the detection of per- and polyfluoroalkyl substances (PFAS). PFAS are a class of "forever chemicals" that have widespread contamination in the environment and pose significant human health risks. The funding will enable the awardee, Pearlhill Technologies LLC, to...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), is supporting research to investigate the long-term metabolic, vascular, and bone health effects of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) mixtures. The $463,850 award to Brown University will leverage the New England Family Study (NEFS) cohort to measure PFAS concentrations in stored pregnancy and adult serum samples. The researchers will then determine if prenatal PFAS burden is associated with adverse metabolic, vascular, and bone health outcomes in mid-adulthood, independent of current PFAS exposures. They will also explore whether diet quality and physical activity levels may mitigate any adverse PFAS-related health impacts. This research aims to address critical knowledge gaps regarding the long-term public health consequences of widespread PFAS exposures and identify potential interventions to reduce associated health risks. The award period is from September 10, 2025 to September 9, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $463.9k | 9/9/25 |