This federal Project Grant award of $567,093 from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports a research project to investigate the impact of wildfire exposure on the human methylome and health.
The key objectives are to: 1) develop comprehensive wildfire exposure data for a cohort of 5,000 adults in Northern California, 2) collect additional health, lifestyle and exposure data from the cohort, and 3) conduct a pilot study of 400 cohort members to evaluate the relationship between wildfire smoke exposure and changes to DNA methylation, including epigenetic estimates of biological age.
The research aims to identify biomarkers of wildfire exposure, explore longitudinal health outcomes, and understand adaptation in populations exposed to increasing wildfire risk due to climate change. The project will be conducted by the University of California, Berkeley, with the work performed in California over the 2-year award period from March 2025 to March 2027.
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