The Trustees of Columbia University in the City of New York, through its Health Sciences Division, was awarded a Project Grant in the amount of $218,862 from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program. The funded project aims to:
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Develop sensitivity analysis approaches to detect and assess the impact of unmeasured confounding bias in estimating the effects of environmental mixtures, single pollutants, and their interactions, while accounting for uncertainty in the unmeasured confounding structure and strength.
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Apply these new methodological approaches to analyze a birth cohort of Bangladeshi mother-infant pairs to characterize the joint effect of metal exposures on child development.
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Create and disseminate user-friendly software to enable widespread application of the developed methods in environmental epidemiology research.
The project period spans from September 6, 2024 to August 31, 2026, with the goal of addressing key methodological gaps in causal inference for observational environmental mixture studies affected by unmeasured confounding.
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