Project Grant R21ES036375
Award Date
9/19/24
Completion Date
8/31/26
Dollars Obligated
$471K
Federal Agency
National Institute of Environmental Health Sciences
Federal Grant Program
93.113
Assistance Type
Project Grant
Place of Performance
Denver, CO 80206, USA
Similar Awards
This $2,413,505 Project Grant awarded by the National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) aims to develop predictive models for beryllium sensitization (BES) and chronic beryllium disease (CBD). The primary goals are to: 1) Characterize the lung compartment-specific gene-protein changes linked to BES and CBD using advanced transcriptomic and proteomic analyses of bronchoalveolar lavage (BAL)...
This federal Project Grant award, totaling $1,054,600.00, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program. The award supports research to investigate the mechanisms driving the development of fibrosis in silicosis and asbestosis, which are progressive lung diseases caused by exposure to silica dust and asbestos. The key objectives of the research project are to: 1) Define distinct subsets of...
This $671,165 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program supports research to identify genetic mechanisms underlying maladaptive respiratory responses to air pollution, particularly ozone exposure. The project aims to use a mouse model to understand how differences in alveolar macrophage gene expression and epigenetic regulation influence the ability to adapt to repeated ozone...
The National Institute of Environmental Health Sciences (NIEHS) awarded Canairy LLC a Project Grant under the Environmental Health (CFDA 93.113) federal grant program. The $324,770 award, which runs from September 2024 to September 2025, supports the development of a stand-alone wearable device to track environmental exposures and assess respiratory functions for patients with chronic obstructive pulmonary disease (COPD). The device will collect data on personal exposure to pollutants and...
This $440,000 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports research at Northwestern University to create an unbiased and global map of the cellular response to environmental proteotoxic stress. The project will integrate cutting-edge chemical-genetic screening with computational analysis to identify critical components, functions, and regulatory nodes in the proteostasis network that cells...
This federal Project Grant award for $720,855 was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program. The award supports the "ENDS Aerosol Particle Deposition, In Utero Exposures and Children's Respiratory Health Effects (ENDURE)" consortium to investigate the effects of in utero exposure to electronic nicotine delivery system (ENDS) aerosols on offspring respiratory health. Key products and services under...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $102,399 to Wright State University to investigate the role of extracellular, UV-damaged DNA in triggering systemic inflammatory responses in photosensitive autoimmune disorders like lupus. The research aims to demonstrate the presence of cyclobutane pyrimidine dimers (CPDs) in extracellular vesicles and correlate this DNA damage with...
The National Institute of Environmental Health Sciences (NIEHS) awarded Emory University a 5-year, $599,416 Project Grant under the Environmental Health (CFDA 93.113) federal grant program. The grant will fund the development, testing, and application of new statistical methods to address analytical challenges in environmental epidemiology research. Key objectives include: 1) utilizing fine-scale exposure data in health analyses, 2) identifying individual and area-level risk factors for...
This $379,504 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program will support research to understand the tissue-specific development of toxicity in response to transgenerational chronic arsenic exposures. The project aims to: (1) detect tissue-specific arsenic uptake using laser-ablation-ICP-MS; (2) identify tissue-specific gene expression changes in response to transgenerational arsenic exposure using RNA...
The National Institutes of Health National Institute of Environmental Health Sciences awarded a $924,612 Project Grant to the California State University, East Bay Foundation, Inc. under the Environmental Health (CFDA 93.113) federal grant program. The grant will fund research from August 2022 to July 2025 to advance chemical risk assessment and predictive toxicology through the development, validation and integration of high-throughput mechanistic in vitro assays. Specifically, the grantee will...