Project Grant R21EB034113
- This Project Grant award, valued at $595,353 and issued on February 1, 2025 by the National Institute of Biomedical Imaging and Bioengineering (NIBIB), supports the development of ultrasensitive ion-selective optodes for self-testing of blood electrolytes. The goal is to create a novel colorimetric sensor capable of detecting electrolyte levels in just a few microliters of whole blood, revolutionizing the self-monitoring of chronic conditions like hypoparathyroidism and congestive heart failure....
- This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286) provides $418,284 to the Georgia TECH Research Corp to evaluate the performance of a new ion sensor-integrated central venous catheter (CVC) and an automated system for real-time correction of electrolyte imbalances. The research project aims to replace traditional...
- This $360,320 Project Grant awarded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) aims to develop and test the first continuous electrochemical sensors for monitoring large protein and peptide analytes, such as insulin and cardiac markers. The project, titled "Aptamer Tagging with Redox Quenchers: A Critical Breakthrough in the Sensitivity of...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $413,067 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to Colorado State University to develop a new class of electrochemical biosensors that use engineered binding proteins. The goal is to simplify fabrication and improve performance of electrochemical sensors, which have potential for inexpensive, sensitive, and quantitative...
- The National Science Foundation (NSF) awarded a three-year, $449,999 Project Grant under their Engineering program (CFDA 47.041) to the University of Cincinnati to develop an implantable biosensor platform that can continuously monitor various biomarkers in the body for over a year. The project aims to create a new class of long-lasting aptamer-based sensors protected by robust porous oxide coatings, which would enable the first practical implantable monitoring system for managing chronic...
- This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $379,730 to the University of North Carolina at Chapel Hill to develop a continuous electrochemical sensor for monitoring therapeutic monoclonal antibodies, using the FDA-approved drug bevacizumab as an example. The research aims to overcome challenges in discriminating between therapeutic antibodies and human IgG in biological fluids, and in regenerating the aptamer binding site for...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $359,995 Project Grant under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program to Clemson University. The funding supports the development and validation of a novel X-ray visualized immunosensor (X-VIS) that can be attached to implanted medical devices to detect and monitor local infection biomarkers. The project aims to fabricate a...
- This $400,000 Project Grant from the National Science Foundation's Division of Electrical, Communications and Cyber Systems, under the Engineering (47.041) federal grant program, will fund research at Georgia Tech Research Corporation to advance implantable bioelectronics for continuous monitoring of vascular health. Specifically, the grant will support understanding of printing soft microstructures for enhanced sensor sensitivity, study of passive wireless sensing principles and 3D...
- This National Science Foundation Project Grant of $395,312 will fund the development of shape-encoded electrokinetic particles for multiplexed biosensing through June 2027. Under the NSF Engineering Directorate's CFDA 47.041 program, the University of Colorado Boulder will work to advance biosensing technologies that can detect heterogeneous biomarkers from blood in a single assay. Specifically, the university will study how biomarker size, charge density, and concentration influence the induced...
- This $268,500 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research program) will support the "Incident Hemodialysis Electrolyte Analysis and Rhythm Trends (IHEART)" study conducted by Dr. Katherine Ravi at Brigham & Women's Hospital. The study aims to investigate how cardiac rhythm morphology associated with sudden cardiac death evolves during the early stages of...
This $426,938 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health aims to develop self-calibrating ion-selective electrodes for at-home monitoring of blood electrolytes. The 2-year grant to Virginia Commonwealth University (VCU) will focus on designing portable, transportable, and mass-producible Ca2+ and K+ sensors that can provide accurate and precise electrolyte measurements without requiring complicated fluidic calibration systems. The research will leverage 3D printing and microfabrication techniques to create self-calibrating sensors that can enable frequent, minimally invasive electrolyte monitoring to support self-management of chronic conditions like heart, kidney, and nerve disorders. The project seeks to overcome the calibration challenges that have hindered the adoption of new decentralized electrolyte monitoring modalities in healthcare practice.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $426.9k | 7/20/23 |