Project Grant R21DC022690
Award Date 1/1/26
Completion Date 12/31/27
Dollars Obligated $438K
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
La Jolla, CA 92093, USA
Similar Awards
- This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $767,494 to the University of Miami to develop human inner ear organoid platforms for studying genetic hearing loss and vestibular disorders. The key objectives are to: 1) establish and optimize human induced pluripotent stem cell-derived 3D inner ear organoid systems from patients with...
- This $249,000 Project Grant award was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD), under the federal Research Related to Deafness and Communication Disorders (CFDA 93.173) program. The grant aims to investigate the role of macrophages, the primary immune cells in the inner ear, in regulating the blood-labyrinth barrier permeability in response to cisplatin-induced ototoxicity. The research will identify the mechanisms by which macrophages contribute...
- This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), aims to establish a comprehensive molecular and physiological biorepository of the human inner ear. The $445,956 award to Vanderbilt University Medical Center will support the collection of inner ear tissues, including the cochlea and vestibular apparatus, as well as non-invasive physiological...
- This federal Project Grant award, totaling $249,000.00, was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The grant supports the development of a CRISPR-based toolkit to investigate the roles of various transcription factors in the development of hair cells, the specialized sensory cells of the inner ear, using an in vitro inner ear organoid model. The project aims...
- The federal Project Grant award of $415,743.00 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research by Oregon Health & Science University (OHSU) on the origins and roles of macrophages in the development, homeostasis, and repair of the tympanic membrane (eardrum). The 5-year project, commencing on February 1, 2025, aims to investigate the fundamental...
- This federal Project Grant award, valued at $514,546.00 and awarded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research to improve the diagnosis and treatment of benign paroxysmal positional vertigo (BPPV) and related labyrinth disorders. The project, conducted by the University of Utah, aims to achieve this goal through quantifying anatomical variance in the...
- This federal Project Grant award of $637,500.00 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program. The goal of the project is to understand the forward transduction that drives inner and outer hair cell stereocilia, as well as the reverse transduction that amplifies the organ of Corti motion via outer hair cell electromotility in human cochleae. The research team...
- This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the federal grant program "Research Related to Deafness and Communication Disorders" (CFDA 93.173), funds research to investigate the role of lipid flippases in the function and degeneration of sensory hair cells in the inner ear. The $115,707 award to the University of Virginia aims to define the developmental timeline and localization of the lipid flippase ATP8B1 and...
- The Project Grant award of $461,250.00 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program, supports an immunological investigation of Meniere's disease at Yale University. The research project aims to confirm preliminary data on the upregulation of specific pathways, including druggable TNF alpha and mTOR pathways, in Meniere's disease, and to establish that...
- This Project Grant award of $427,625 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The objective is to establish the posterior lateral line (PLL) ganglion of larval zebrafish as a model system for studying neuronal repair and replacement in the inner ear. The researchers aim to determine the contributions of neural precursor cell populations to ongoing...