Project Grant R21CA313410
Award Date 6/2/26
Completion Date 5/31/28
Dollars Obligated $445K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
New York, NY 10065, USA
Similar Awards
- Federal Project Grant Award Summary The National Cancer Institute awarded a Project Grant of $495,715 to the Sloan-Kettering Institute for Cancer Research under the Cancer Biology Research program (CFDA 93.396) on August 5, 2025, with a completion date of July 31, 2030. This award funds fundamental research to decipher the pathogenesis and therapeutic vulnerabilities in germline RUNX1-mutated acute myeloid leukemia (AML). The research focuses on understanding how germline RUNX1 mutations...
- Federal Project Grant Award Summary The National Cancer Institute awarded $1,034,176 to Sloan-Kettering Institute for Cancer Research under the Cancer Biology Research program (CFDA 93.396) on August 18, 2025, for a project extending through July 31, 2032. The research focuses on understanding and targeting aberrant RNA splicing in leukemia, building on the principal investigator's 13-year track record of discovering genetic alterations in hematopoietic malignancies. The project aims to...
- Federal Project Grant Award Summary The National Cancer Institute awarded a Project Grant of $418,176.00 to Sloan-Kettering Institute for Cancer Research under the Cancer Biology Research program (CFDA 93.396) for the period September 1, 2025, through August 31, 2028. This three-year award supports the advanced development and validation of programmable nucleic acid cytometry, a technology designed to isolate and profile rare cell populations from tumors and tissues. Building on the...
- Federal Grant Award Summary The National Cancer Institute awarded Sloan-Kettering Institute for Cancer Research $1,467,021 under the Cancer Treatment Research program (CFDA 93.395) for a five-year project running from April 1, 2026 through March 31, 2031. This project focuses on identifying and targeting tumor regenerative cells (TRCs) that drive treatment resistance and metastatic recurrence in locally advanced rectal cancer (LARC) patients undergoing total neoadjuvant therapy (TNT). Through...
- Federal Grant Award Summary The National Cancer Institute awarded Sloan-Kettering Institute for Cancer Research a $452,540 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) on July 11, 2025, with a completion date of June 30, 2027. This award supports the development of a novel T-cell imaging paradigm utilizing positron emission tomography (PET) agents targeting CD8 and CD4 markers to provide real-time monitoring of endogenous T-cell trafficking, tumor...
- Federal Project Grant Award Summary The National Cancer Institute awarded Sloan-Kettering Institute for Cancer Research $452,540 under the Cancer Biology Research program (CFDA 93.396) to conduct a two-year research project from May 1, 2026 through April 30, 2028. The project, titled "Innate & Adaptive Determinants of Post-CAR Cytokine Release Syndrome," investigates the mechanisms underlying cytokine release syndrome (CRS)—a severe inflammatory response occurring in 93% of...
- Federal Project Grant Award Summary Albert Einstein College of Medicine received a $561,407 Project Grant award from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396), with an award date of June 18, 2026 and ultimate completion date of May 31, 2031. The project investigates causal mechanisms driving germline predisposition to myeloproliferative neoplasms (MPNs) by elucidating how common genetic variants increase MPN risk through effects on...
- Federal Project Grant Award Summary The National Cancer Institute awarded a $323,860 Project Grant on August 18, 2025, to Sloan-Kettering Institute for Cancer Research under the Cancer Research Manpower program (CFDA 93.398) to support biomedical research training and investigator development in cancer science. The project, titled "Investigating the Role of Mutagenic DNA Repair During the Persistence of Cancer Cells," will be conducted at the Institute's New York facility through April...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded a Project Grant of $716,521 to Sloan-Kettering Institute for Cancer Research on August 25, 2025, under the Cancer Treatment Research program (CFDA 93.395). The award supports the development and clinical evaluation of DLL3-targeted IL18-secreting chimeric antigen receptor (CAR) T cells for treating small cell lung cancer (SCLC). The research initiative addresses a critical clinical need, as SCLC currently demonstrates...
- Federal Project Grant Award Summary The National Cancer Institute awarded $292,028 to Sloan-Kettering Institute for Cancer Research under the Cancer Research Manpower program (CFDA 93.398) beginning August 1, 2025, and concluding July 31, 2030. This five-year Project Grant supports research investigating genome instability associated with focal oncogene amplification (OA) and the development of therapeutic strategies to address treatment-resistant cancers. The research deliverables include...