Project Grant R21CA301112
- Federal Grant Award Summary Kaiser Foundation Hospitals (Kaiser Permanente), through its Kaiser Foundation Research Institute, received a $658,743 Project Grant from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393) awarded on August 25, 2025, with a completion date of July 31, 2030. The grant supports development and validation of prediction models for functional trajectories, cognitive outcomes, and quality of life among adults aged 65 and older...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc., a Project Grant of $734,942 under the Cancer Cause and Prevention Research program (CFDA 93.393) effective August 1, 2025, through July 31, 2030. This project addresses cardiovascular disease (CVD) risk in breast cancer survivors by generating novel DNA methylation biomarker data from the Pathways Study, a prospective cohort of 4,504 women diagnosed with...
- Federal Project Grant Award Summary The National Cancer Institute awarded a $825,627 Project Grant to the University of California, Los Angeles, effective May 1, 2026, through April 30, 2031, under the Cancer Cause and Prevention Research program (CFDA 93.393). The award funds development of advanced computational models designed to improve breast cancer prognosis by integrating whole slide imaging (WSI) pathology data with clinical prognostic factors. The research deliverables include: (1)...
- Federal Grant Award Summary Kaiser Foundation Hospitals, operating as Kaiser Permanente, received a $733,410 Project Grant from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393) awarded August 1, 2026, with completion targeted for July 31, 2031. The grant supports research evaluating the real-world impact of incretin mimetics, particularly glucagon-like peptide-1 (GLP-1) receptor agonists, on cancer risk among patients with obesity and type 2...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded the University of Pittsburgh a $649,620 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) for the period May 1, 2026 through April 30, 2031. This research project addresses gaps in understanding how Medicare Advantage coverage impacts cancer care access, quality, and outcomes for older adults. The study will analyze insurance-related barriers to specialty cancer care by examining coverage...
- Federal Grant Award Summary The University of Kansas Medical Center Research Institute, Inc. received a $135,951 Project Grant from the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395), awarded September 4, 2025, with completion targeted for August 31, 2030. This grant supports research to enhance access to breast cancer prevention clinical trials, addressing well-documented barriers including insufficient population representation, limited awareness of...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Johns Hopkins University a Project Grant totaling $130,301 on September 5, 2025, under the Cancer Cause and Prevention Research program (CFDA 93.393). The award supports research extending the Surveillance, Epidemiology, and End Results (SEER)-Medicare Database, a critical population-based health services resource that links Medicare claims data with cancer registry enrollment information. The research will leverage...
- Federal Grant Award Summary Mayo Clinic received a $722,914 Project Grant from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393) awarded June 1, 2026, with a completion date of May 31, 2031. The grant supports research to extract and validate radiomic phenotypes—high-throughput imaging features reflecting tissue structure complexity—from three-dimensional digital breast tomosynthesis (DBT) screening exams. The primary deliverable is the...
- Federal Grant Award Summary Duke University's Office of Research Administration received a $616,652 Project Grant from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393) effective July 1, 2026, through June 30, 2031. The project addresses a critical clinical gap by developing the first prognostic classification system for patients with recurrent breast cancer (RBC). The primary deliverable is a multi-institutional tumor registry leveraging...
- Federal Grant Award Summary The National Cancer Institute awarded H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc. a Project Grant under the Cancer Research Manpower program (CFDA 93.398) in the amount of $123,182.00, effective July 17, 2025, with a completion date of June 30, 2027. This award supports a Pathway to Independence Award (K99/R00) research project investigating the mechanisms by which dormant disseminated breast cancer cells communicate with their surrounding...
The National Cancer Institute (NCI), under its Cancer Cause and Prevention Research program (CFDA 93.393), awarded a $440,440 Project Grant to Kaiser Foundation Hospitals' Kaiser Permanente Research Institute for the period August 1, 2026 through July 31, 2028. The grant supports the development of a statistical framework and risk prediction model designed to identify breast cancer survivors at elevated risk of surveillance mammography failure—specifically, those with greater likelihood of missing second breast cancer recurrence during routine surveillance examinations. The research addresses a critical clinical gap where current surveillance mammography achieves only 70.4% sensitivity in breast cancer survivors, resulting in missed cancer detection in approximately 30% of cases. The project delivers a methodological and analytical product addressing data challenges inherent in electronic health records (EHR) analysis, particularly the irregular observation patterns and outcome-dependent surveillance scheduling that characterize breast cancer follow-up care. The developed risk prediction model will enable more efficient allocation of supplemental imaging resources (such as magnetic resonance imaging and whole breast ultrasound) to survivors with the greatest clinical need, thereby improving early detection outcomes and reducing morbidity and mortality in the breast cancer survivor population of over 4 million individuals in the United States.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $440.4k | 6/9/26 |