This Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) provides $230,010 to the University of Chicago to conduct research aimed at unraveling the mechanisms driving metastasis in small cell lung cancer (SCLC). The research strategy integrates human pluripotent stem cell-derived SCLC models, clinical samples, patient-derived xenografts, and advanced technologies like single-cell sequencing to investigate the cellular and molecular drivers behind SCLC's aggressive metastatic potential. By examining cell behavior in both primary tumors and metastatic sites, the project aims to gain essential insights that could lead to novel diagnostic and therapeutic approaches for this highly lethal form of cancer. The award has an initial term from Mar 1, 2025 to Feb 28, 2027.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $0 | 2/12/25 | ||
| Not listed | $230.0k | 1/30/25 |