This federal Project Grant award, totaling $399,829.00, was provided by the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) to the University of Washington. The objective is to develop a generalizable model of normal tissue recovery to enable personalized re-irradiation for cancer patients. The research aims to: 1) quantify the evolution of normal tissue damage and recovery after radiation therapy using imaging biomarkers, and 2) explore the feasibility of personalizing re-irradiation plans based on the observed normal tissue response from the initial radiation treatment. This work addresses the lack of data and conceptual framework to guide clinical re-irradiation, which is increasingly needed as more patients receive multiple radiation treatments. The University of Washington will conduct this research over a 2-year period from July 2024 to June 2026.
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