The National Cancer Institute awarded a 4-year, $300,374 Project Grant (R01CA288301) under the Cancer Cause and Prevention Research program (CFDA 93.393) to the University of South Dakota to develop and test a mobile web app intervention for promoting cervical cancer screening among indigenous women. The goal is to increase screening rates and reduce disparities in cervical cancer morbidity and mortality in this population. The project will involve a 2-arm randomized controlled trial with 120...
This Cooperative Agreement award of $303,875 from the National Cancer Institute (NCI), under the CFDA 93.393 Cancer Cause and Prevention Research program, aims to discover and develop natural products as cancer interception agents for colorectal cancer. The key objectives are to:
Establish high-throughput screening assays to identify natural product fractions that selectively inhibit the cancer-related targets MPGES-1, 5-LOX, and ODC. Secondary assays and organoid studies will further...
The National Cancer Institute (NCI) awarded a $1,226,040 Project Grant under the Cancer Cause and Prevention Research (CFDA 93.393) program to the Regents of the University of Minnesota to conduct a randomized clinical trial of a culturally-tailored suite of smoking cessation resources for American Indian persons.
The project aims to: 1) Co-create a culturally-aligned website, "Smokefree.gov for Natives," to serve as the landing page for online cessation treatment content and...
The Project Grant award of $1,072,500 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) is supporting cancer research initiatives at the University of Oklahoma (OU) Univ Of Oklahoma Health Sciences Center Division. The primary objective is to advance cancer research in Oklahoma, particularly focused on serving diverse communities, including Native American populations.
During this Phase III award, OU aims to build...
This federal Project Grant award of $624,697, provided by the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) to the University of Kansas Medical Center Research Institute, Inc., will fund a study to compare the implementation of a colorectal cancer (CRC) screening decision-making tool ("I2 tool") through two approaches: a Normalization Process Theory-guided Participatory Learning in Action (NPT-PLA) process versus a standard quality improvement...
This $224,099 Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) aims to develop a targeted colorectal cancer (CRC) screening strategy for adults ages 45-49 to maximize screening uptake and prevent cancer disparities. The key objectives are to:
Characterize the acceptability of CRC screening among adults ages 45-49 through a pilot trial and surveys/interviews to identify factors influencing screening uptake.
Conduct a randomized controlled...
This federal Project Grant award from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research (CFDA 93.393) program provides $622,913 to the University of California, Los Angeles (UCLA) to evaluate a multilevel intervention to increase colonoscopic follow-up after abnormal stool-based colorectal cancer screening in a community safety-net setting.
The key products and services to be delivered include:
Conducting a pragmatic, cluster randomized trial at Federally...
This federal Project Grant award of $241,296, awarded by the National Institute on Minority Health and Health Disparities (part of the National Institutes of Health), is focused on advancing cancer health equity for American Indian and Alaskan Native (AI/AN) communities. The grant, awarded under the Minority Health and Health Disparities Research program (CFDA 93.307), will support a multi-pronged effort to:
Utilize whole exome sequencing data from Hispanic/Latino gastric cancer samples to...
This $447,686 Cooperative Agreement award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research program) will establish the first community-engaged cohort study to investigate factors associated with the elevated risk of colorectal cancer among Alaska Native people.
Led by the Alaska Native Tribal Health Consortium (ANTHC) in partnership with the Fred Hutchinson Cancer Center, the 5-year project will enroll 1,000 Alaska Native individuals to collect...
This federal Project Grant award of $328,822 from the National Cancer Institute (NCI) under the CFDA 93.393 Cancer Cause and Prevention Research program supports the development and evaluation of a mobile health (mHealth) platform called the Integrated Cancer Awareness Network (ICAN). The ICAN platform aims to increase cancer screening uptake in India by educating both primary care providers and community members on cancer risk factors, symptoms, and the importance of early detection through...