Project Grant R21AR084297
Award Date
4/10/25
Completion Date
3/31/27
Dollars Obligated
$199K
Awardee
Duke University (TP7EK8DZV6N5)
Federal Grant Program
93.846
Assistance Type
Project Grant
Place of Performance
Connecticut, USA
Similar Awards
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $2,764,642 to The Children's Hospital Corporation (doing business as Boston Children's Hospital) to develop an advanced skin-on-a-chip platform. The goal is to create a more complete and longer-lasting skin organoid culture system that can better mimic normal skin development,...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $343,904 to The Regents of the University of California, San Francisco (UCSF) to investigate genetic differences in atopic dermatitis between Asian and Hispanic populations. The key objective is to identify and validate a set of abnormal transcripts in skin T cells that may serve as...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $526,174 to Duke University to engineer heterocellular human skeletal muscle tissues. The goal is to recreate and study the native stem cell niche function in healthy skeletal muscle, which is critical for regeneration. The research will increase the cellular complexity of the...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support research to investigate the local immune response in the skin during bacterial infections. The goal is to utilize a novel skin-on-a-chip model to gain mechanistic insights into the migration of hematopoietic stem and progenitor cells (HSPCs) into human skin and their ability to produce functional neutrophils in...
This federal Project Grant award of $249,000.00, provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research conducted by The Ohio State University to elucidate the mechanisms by which commensal microbes influence the function of skin-resident myeloid cells, particularly inflammatory monocytes, and their role in immune homeostasis during early life. The...
This Project Grant award for $230,212, provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research to investigate how immune cells in the skin interact with and influence the functional heterogeneity of epithelial stem cells. The project, led by Rockefeller University, aims to: 1) determine how direct contact between dendritic epidermal T cells and hair...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will provide $401,433 from September 2023 to August 2025 to support research at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. The research aims to investigate the role of protein O-GlcNAcylation in regulating keratinocyte function and its impact on skin...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under CFDA program 93.846 Arthritis, Musculoskeletal and Skin Diseases Research, provides $706,710 to Virginia Commonwealth University (VCU) to conduct research on the role of sphingolipid biosynthesis in the epidermal barrier, including its function in healthy skin and diseases like atopic dermatitis. The research aims to investigate how the unique species of sphingoid backbones...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $383,570 to Temple University to conduct research on interleukin-36 (IL-36) cytokine activation and inactivation mechanisms. The project aims to improve understanding of IL-36 functions and their role in inflammatory conditions, such as atopic dermatitis, psoriasis, and skin infections,...
This $144,362 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) supports research into the long-term systemic consequences of type 2 skin inflammation on epithelial stem cells. The research aims to define the cell-intrinsic mechanisms and niche signaling that establish epithelial stem cell hyperresponsiveness following exposure to the inflammatory alarmin...