Project Grant R21AI202145
- Federal Grant Award Summary Virginia Polytechnic Institute & State University received a $611,861 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period September 1, 2025 through August 31, 2030. The project investigates chromosomal rearrangements in Aedes aegypti mosquitoes, the primary vector for dengue, Zika, and other arboviral diseases affecting approximately...
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $191,163 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 5, 2026 through January 31, 2028. The grant supports research on the transmission dynamics and pathogenesis of contemporary Mayaro virus (MAYV) strains, an emerging arbovirus endemic to...
- Federal Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $452,769 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 11, 2025, to conduct research on the impact of BDGR-49 treatment on Venezuelan Equine Encephalitis Virus (VEEV) induced neurological sequelae. The research addresses a critical public health gap by...
- Federal Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $240,549 Project Grant from the National Science Foundation (NSF) Division of Environmental Biology under the Biological Sciences program (CFDA 47.074), effective August 1, 2026 through July 31, 2029. This collaborative research initiative develops the first comprehensive evolutionary and ecological framework for anopheline mosquitoes by integrating phylogenomic analysis, morphological...
- Federal Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $432,155 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded June 11, 2026, with completion scheduled for May 31, 2028. The research focuses on understanding how coinfection with bacterial pathogens affects West Nile Virus (WNV) transmission dynamics in songbirds,...
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $422,355 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 23, 2025, with completion targeted for June 30, 2027. The grant funds mechanistic and structural studies examining the signaling histidine kinase GacS from Pseudomonas aeruginosa, a nosocomial...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Virginia Polytechnic Institute & State University a $421,560 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct basic research on Brucella virulence mechanisms. The award, issued June 12, 2026, with completion targeted for May 31, 2028, supports research characterizing an alternative genetic pathway critical to Brucella pathogenesis,...
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received an $808,607 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 9, 2026, with a completion date of June 30, 2031. The grant supports research to develop and optimize AI-designed antimicrobial peptides targeting ESKAPE pathogens (Enterococcus faecium, Staphylococcus...
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $225,846 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 12, 2026, with completion targeted by May 31, 2028. The project advances antivirulence therapeutic strategies to combat antibiotic resistance by developing small-molecule inhibitors targeting Type IV Pili...
- Federal Grant Award Summary Texas Tech University received a $648,891 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 3, 2026, with completion targeted for January 31, 2031. The project investigates population dynamics and genetic structure of Aedes aegypti mosquitoes—the primary vector of dengue and yellow fever viruses—at the invasive front in the American Southwest...
Virginia Polytechnic Institute & State University (Virginia Tech) received a $208,641 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 16, 2026, with completion targeted for June 30, 2028. The project, titled "The 'Hidden' Proteins in Aedes Aegypti," will systematically discover and characterize microproteins encoded by long non-coding RNAs (lncRNAs) in the dengue vector mosquito Aedes aegypti. The research addresses a critical gap in mosquito biology knowledge by leveraging ribosome sequencing (Ribo-seq) and complementary genomic approaches to identify previously uncharacterized small open reading frames (sORFs) that encode functional microproteins. The project will deliver two primary research outputs: comprehensive discovery of lncRNA-encoded microproteins in Aedes aegypti through systematic and complementary methodologies, and functional characterization of selected microproteins to determine their biological roles in mosquito development, physiology, and metabolism. This research supports enhanced vector control strategies by identifying novel molecular targets for managing mosquito-borne diseases including dengue, chikungunya, yellow fever, and Zika—diseases for which current prevention relies primarily on insecticide-based vector control now complicated by widespread insecticide resistance. The work will be conducted at Virginia Tech's Blacksburg, Virginia campus and contributes to the broader NIAID portfolio of biomedical research addressing infectious disease threats.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $208.6k | 7/16/26 |