Project Grant R21AI199873
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Scripps Research Institute a $506,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 9, 2025, with a completion date of June 30, 2027. The award supports the development of high-throughput technologies for generating and screening small interfering RNA (siRNA)-peptide conjugates designed to improve delivery efficiency for viral infection...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Scripps Research Institute a $919,605 Project Grant on June 10, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This grant supports antibody-guided vaccine development research targeting human astrovirus (HAstV), a leading cause of viral diarrhea in children and a significant public health concern globally. The project will deliver comprehensive monoclonal...
- Federal Project Grant Award Summary The Scripps Research Institute received a $1,379,954 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 21, 2025, with completion targeted for July 31, 2030. The award supports systematic research to engineer durable immunity through optimization of Human Immunodeficiency Virus (HIV) vaccine parameters designed to drive...
- Federal Project Grant Summary Award Information: The National Institute of Allergy and Infectious Diseases (NIAID) awarded $899,741 to Scripps Research Institute through the Allergy and Infectious Diseases Research program (CFDA 93.855) on April 1, 2026, with a completion date of March 31, 2031. Products and Services: Under this five-year Project Grant, Scripps Research Institute will develop a long-acting injectable (LAI) therapy for hepatitis B virus (HBV) in individuals co-infected with human...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $438,500 Project Grant to the University of California, San Diego under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 8, 2025, with a completion date of June 30, 2027. This award funds investigator-initiated biomedical research examining the sequence-specific determinants and impacts of NS2 (nonstructural protein 2) interactions with the Influenza A Virus...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Scripps Research Institute a Project Grant totaling $931,385 under the Allergy and Infectious Diseases Research program (CFDA 93.855), with an award date of June 10, 2026 and completion date of May 31, 2027. The grant funds research and development of glycoengineered HIV-1 envelope (Env) vaccine immunogens incorporating core α(1,3)-fucose motifs to enhance vaccine efficacy. The...
- Federal Grant Award Summary The Scripps Research Institute received a $230,000 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective May 1, 2026 through April 30, 2028. The grant supports the development of a modular crosslinking mass spectrometry (XL-MS) platform designed to enable quantitative, proteome-wide mapping of protein-protein interactions (PPIs) in live cells without...
- Federal Grant Award Summary Award Details: The Scripps Research Institute received a $511,531 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 13, 2026 through January 31, 2031. Products and Services: This project advances HIV vaccine development by incorporating engineered transmembrane envelope (Env) glycoprotein vaccine candidates into stable lipid nanodiscs using...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Scripps Research Institute a Project Grant totaling $1,285,304 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop and evaluate an enhanced HIV vaccine regimen capable of producing durable broadly neutralizing antibody (BNAB) responses. The research, which commenced August 1, 2025, and extends through July 31, 2030, leverages a novel six-shot germline-targeting...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Scripps Research Institute a $3.02 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) beginning August 8, 2025, with a completion date of July 31, 2029. This award supports the design and development of single-shot sequential immunization regimens for HIV using atomic layer deposition (ALD) technology. The research builds upon preclinical successes...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded Scripps Research Institute a Project Grant totaling $270,443 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective June 23, 2026, with an ultimate completion date of May 31, 2028. This research initiative focuses on characterizing host-specific profiles of defective viral genomes (DVGs) in influenza virus strains, with particular emphasis on understanding how DVGs modulate viral pathogenicity and immune responses. The research builds on secondary analysis of genomic sequencing data from highly pathogenic avian influenza (H5N1) samples, examining DVG formation patterns in viral polymerase segments (PB2, PB1, and PA) and correlating these patterns with viral fitness, disease severity outcomes, and vaccine effectiveness. The funded research aims to advance scientific understanding of how DVG abundance and characteristics vary across host species and infection contexts, with implications for predicting influenza strain pathogenesis and informing public health preparedness strategies. Deliverables include scientific analysis, characterization of DVG profiles, and research findings that contribute to the broader knowledge base regarding the role of defective viral genomes in respiratory viral pathogenesis—knowledge applicable to influenza A virus, respiratory syncytial virus (RSV), and SARS-CoV-2. The project will be conducted at Scripps Research Institute's La Jolla, California facility.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $270.4k | 6/23/26 |