Project Grant R21AI198155
- Summary of Federal Project Grant Award The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $1,498,650 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective May 15, 2025, through April 30, 2027. This award supports investigator-initiated biomedical research examining mechanisms controlling HIV-1 cellular reservoirs in memory CD4+ T cells. Specifically, the research project investigates how the BACH2...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University $650,934 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct a mechanistic study examining how HIV-1 Gag/matrix protein sequesters the CARD8 inflammasome. The research project, which commenced August 1, 2025 and concludes July 31, 2026, combines structural, biochemical, and functional approaches to elucidate the molecular interaction...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $427,623 Project Grant to The Washington University in St. Louis under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 24, 2026, with a completion date of January 31, 2028. This research award funds investigative work examining how HIV-induced immunometabolic perturbations impair tuberculosis (TB) immunity in people living with HIV (PLWH), even when HIV is...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a $638,220 Project Grant effective April 1, 2026, through March 31, 2031, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports investigator-initiated biomedical research examining DNA ADP-ribosylation mechanisms in bacterial-phage interactions. The research focuses on understanding how bacteria utilize DNA-targeting...
- Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $107,542 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period September 1, 2025, through August 31, 2027. The award supports investigator-initiated biomedical research examining the differential sorting and trafficking mechanisms of Plasmodium falciparum secreted proteins, with particular focus on how...
- Federal Project Grant Award Summary The University of Wisconsin-Madison received a $475,681 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 1, 2026 through January 31, 2031. The award funds the development and validation of novel analytical tools and methodologies to characterize HIV-1 alternatively spliced transcript functionality. Specifically, the project will...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a $777,360 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, through July 31, 2030. This award funds research titled "Advancing Lymphatic Filariasis Elimination with Parasite Genomic Epidemiology," which will deliver comprehensive genomic analysis and characterization of Wuchereria bancrofti...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $427,625 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 2, 2026, with a completion date of January 31, 2028. The award supports investigator-initiated biomedical research examining viral infection sensing mechanisms in Caenorhabditis elegans (C. elegans), a model organism system. The research will...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $773,053 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective June 6, 2025, with a completion date of May 31, 2030. This research project focuses on elucidating the biosynthesis of beta-1,6-glucan in the cell wall of Cryptococcus neoformans, a fungal pathogen responsible for approximately 150,000 deaths annually,...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $151,040 to The Washington University (Office of Sponsored Research Services) on December 23, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research will be conducted through June 30, 2028, at the university's location in Missouri. This award supports investigator-initiated biomedical research addressing infectious disease...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $427,626 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period April 1, 2026 through March 31, 2028. This research project, titled "Identification of Host Factors That Mediate the Nuclear Retention of Unspliced and Partially Spliced HIV-1 Transcripts," focuses on fundamental virology research aimed at elucidating the mechanisms by which HIV-1 viral transcripts lacking complete splicing remain sequestered in the cell nucleus. The project delivers scientific research intended to identify and characterize host cell factors responsible for nuclear retention of HIV-1 RNA transcripts that have not undergone complete alternative splicing. The research will investigate minimal sequence features necessary and sufficient for nuclear retention and determine whether specific trans-acting host factors mediate this process. By advancing understanding of HIV-1 transcript trafficking mechanisms, this research contributes to the broader body of knowledge on viral pathogenesis and may inform future therapeutic strategies targeting HIV-1 replication and persistence.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $427.6k | 4/1/26 |