Project Grant R21AI197491
- Federal Grant Award Summary Emory University received a $778,829 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective June 2, 2025, through May 31, 2030. The award funds a comprehensive research initiative to characterize early-life B-cell and antibody-secreting cell (ASC) development in the human spleen, with particular focus on understanding how naturally occurring plasma...
- Federal Grant Award Summary Emory University received a $941,106 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 7, 2025, through June 30, 2027. The grant funds basic biomedical research investigating the genetic regulation of Factor VIII (FVIII) inhibitor development in hemophilia A patients. The research employs Diversity Outbred mice—an outbred population derived...
- Federal Project Grant Award Summary Emory University received a $160,546 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 3, 2025, with a completion date of August 31, 2029. The award supports research toward developing foundation epidemic models for respiratory infections through a novel spatiotemporal machine learning framework. This research initiative will be...
- Federal Project Grant Award Summary Emory University received a $356,389 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective May 18, 2025, with completion targeted for June 30, 2026. The project, titled "Investigating the Role of Intrahepatic Plasma Cells in the Clearance of HCV Infection: Implications for Rational Vaccine Design," delivers investigator-initiated...
- Federal Grant Award Summary Emory University received a $711,555 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective May 13, 2025, through April 30, 2030. The project delivers an integrated research and development framework combining graph neural networks with traditional compartmental models to advance understanding of spatiotemporal transmission dynamics and control...
- Federal Grant Award Summary Emory University received a $246,562 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective June 27, 2025 through January 31, 2028. The award supports research investigating the fundamental mechanisms underlying beneficial effects of influenza A virus (IAV) co-infection in host cells. The principal investigator will generate a panel of viral variants...
- Federal Project Grant Award Summary Emory University received a $1,332,155 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded June 10, 2025, with a completion date of May 31, 2030. The grant supports systematic research to optimize broadly neutralizing antibody (BNAb) immunotherapies combined with antiretroviral therapy (ART) for HIV cure in infants with perinatal infection, with...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $416,276.00 to the University of Georgia Research Foundation under the Allergy and Infectious Diseases Research program (CFDA 93.855) on May 5, 2025, with completion targeted for April 30, 2030. This project grant supports research aimed at enhancing the protective capacity of antibodies by optimizing Fc-mediated immune responses. The research investigates multiple factors that...
- Federal Grant Award Summary Emory University received a $653,693 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on May 12, 2025, with a completion date of April 30, 2026. This grant supports structural research on the HIV-1 virion and the mechanism of action of the capsid-targeting compound lenacapavir. The research deliverables include advanced structural characterization of...
- Federal Project Grant Award Summary The University of Chicago received a $3.02 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 8, 2025, with a completion date of June 30, 2029. This research project investigates the role of BRWD1-mediated cohesin conversion in B cell biology, specifically examining how this epigenetic mechanism coordinates genomic diversity with...
Emory University received a $412,749 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 6, 2026, with completion targeted for January 31, 2028. The research project, titled "Identification of Enhancers That Facilitate Genetic Manipulation of Specific B-Cell Subsets," aims to develop genetic tools and methodologies to interrogate the heterogeneity and molecular properties of memory B cells (MBCs) and antibody-secreting plasma cells (ASCs). The project will characterize cis-regulatory elements (enhancers) that control cell-type-specific gene expression during B-cell differentiation, leveraging epigenetic analyses and preliminary datasets to identify enhancers active in specific B-cell subsets, including immunoglobulin A (IgA) ASCs and extrafollicular MBCs. The research deliverables will include identification and characterization of cell-type-specific enhancers suitable for precise genetic manipulation of defined B-cell populations, enabling more detailed phenotypic analysis of functionally diverse MBC and ASC subsets than current Cre-Lox mouse models permit. This project supports fundamental immunological research that advances scientific understanding of humoral immune responses and provides tools for future vaccine development and therapeutic intervention strategies targeting specific B-cell populations.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $412.7k | 2/6/26 |